Differential Patterns and Outcomes of 20.6 Million Cardiovascular Emergency Department Encounters for Men and Women in the United States

被引：13

作者：

Raisi-Estabragh, Zahra ^{[1
,2
]}

Kobo, Ofer ^{[3
,4
]}

Elbadawi, Ayman ^{[5
]}

Velagapudi, Poonam ^{[6
]}

Sharma, Garima ^{[7
]}

Bullock-Palmer, Renee P. ^{[8
]}

Petersen, Steffen E. ^{[1
,2
,9
,10
]}

Mehta, Laxmi S. ^{[11
]}

Ullah, Waqas ^{[12
]}

Roguin, Ariel ^{[4
]}

Sun, Louise Y. ^{[13
,14
]}

Mamas, Mamas A. ^{[3
,15
]}

机构：

[1] Queen Mary Univ London, William Harvey Res Inst, Natl Inst Heart Res Barts Biomed Res Ctr, Ctr Adv Cardiovasc Imaging, London, England

[2] Barts Hlth Natl Hlth Serv Trust, Barts Heart Ctr, St Bartholomews Hosp, London, England

[3] Keele Univ, Keele Cardiovasc Res Grp, Keele, Staffs, England

[4] Hillel Yaffe Med Ctr, Dept Cardiol, Hadera, Israel

[5] Baylor Coll Med, Dept Cardiovasc Med, Div Cardiol, Houston, TX USA

[6] Univ Nebraska Med Ctr, Omaha, NE USA

[7] Johns Hopkins Univ, Div Cardiol, Johns Hopkins Ciccarone Ctr Prevent Cardiovasc, Sch Med & Hosp, Baltimore, Maryland, Liberia

[8] Deborah Heart & Lung Ctr, Dept Cardiol, Mills, NJ USA

[9] Hlth Data Res UK, London, England

[10] Alan Turing Inst, London, England

[11] Ohio State Univ, Div Cardiol, Dept Internal Med, Columbus, OH USA

[12] Thomas Jefferson Univ Hosp, Philadelphia, PA 19107 USA

[13] Univ Ottawa, Div Cardiac Anesthesiol, Inst Heart, Ottawa, ON, Canada

[14] Univ Ottawa, Sch Epidemiol & Publ Hlth, Ottawa, ON, Canada

[15] Univ Manchester, Inst Populat Hlth, Manchester, Lancs, England

来源：

JOURNAL OF THE AMERICAN HEART ASSOCIATION | 2022年 / 11卷 / 19期

基金：

英国科研创新办公室;

关键词：

atrial fibrillation; essential hypertension; men; sex characteristics; stroke; United States; women; SEX-DIFFERENCES; CLINICAL PRESENTATION; GENDER-DIFFERENCES; DISEASE; HEALTH; MANAGEMENT;

D O I：

10.1161/JAHA.122.026432

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background We describe sex-differential disease patterns and outcomes of >20.6 million cardiovascular emergency department encounters in the United States. Methods and Results We analyzed primary cardiovascular encounters from the Nationwide Emergency Department Sample between 2016 and 2018. We grouped cardiovascular diagnoses into 15 disease categories. The sample included 48.7% women; median age was 67 (interquartile range, 54-78) years. Men had greater overall baseline comorbidity burden; however, women had higher rates of obesity, hypertension, and cerebrovascular disease. For women, the most common emergency department encounters were essential hypertension (16.0%), hypertensive heart or kidney disease (14.1%), and atrial fibrillation/flutter (10.2%). For men, the most common encounters were hypertensive heart or kidney disease (14.7%), essential hypertension (10.8%), and acute myocardial infarction (10.7%). Women were more likely to present with essential hypertension, hypertensive crisis, atrial fibrillation/flutter, supraventricular tachycardia, pulmonary embolism, or ischemic stroke. Men were more likely to present with acute myocardial infarction or cardiac arrest. In logistic regression models adjusted for baseline covariates, compared with men, women with intracranial hemorrhage had higher risk of hospitalization and death. Women presenting with pulmonary embolism or deep vein thrombosis were less likely to be hospitalized. Women with aortic aneurysm/dissection had higher odds of hospitalization and death. Men were more likely to die following presentations with hypertensive heart or kidney disease, atrial fibrillation/flutter, acute myocardial infarction, or cardiac arrest. Conclusions In this large nationally representative sample of cardiovascular emergency department presentations, we demonstrate significant sex differences in disease distribution, hospitalization, and death.

引用

页数：19