Carbon Dots for Bacterial Detection and Antibacterial Applications-A Minireview

被引:18
作者
Anand, Anisha [1 ]
Manavalan, Gopinathan [1 ]
Mandal, Ranju Prasad [2 ]
Chang, Huan-Tsung [2 ]
Chiou, Yi-Ru [3 ]
Huang, Chih-Ching [1 ,4 ,5 ]
机构
[1] Natl Taiwan Ocean Univ, Dept Biosci & Biotechnol, 2 Beining Rd, Keelung 20224, Taiwan
[2] Natl Taiwan Univ, Dept Chem, Taipei 10617, Taiwan
[3] Natl Changhua Univ Educ, Inst Photon, Changhua 500, Taiwan
[4] Natl Taiwan Ocean Univ, Ctr Excellence Oceans, Keelung 20224, Taiwan
[5] Kaohsiung Med Univ, Coll Pharm, Sch Pharm, Kaohsiung 80708, Taiwan
关键词
Carbon quantum dots; fluorescence; bacterial detection; antimicrobial activity; reactive oxygen species; photoactivation; GRAPHENE QUANTUM DOTS; ONE-STEP SYNTHESIS; PATHOGENIC BACTERIA; NEGATIVE CHARGES; GREEN SYNTHESIS; IN-VITRO; FLUORESCENT; THERAPY; IDENTIFICATION; SPERMIDINE;
D O I
10.2174/1381612825666191216150948
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
The prevention and treatment of various infections caused by microbes through antibiotics are becoming less effective due to antimicrobial resistance. Researches are focused on antimicrobial nanomaterials to inhibit bacterial growth and destroy the cells, to replace conventional antibiotics. Recently, carbon dots (C-Dots) become attractive candidates for a wide range of applications, including the detection and treatment of pathogens. In addition to low toxicity, ease of synthesis and ftmctionalization, and high biocompatibility, C-Dots show excellent optical properties such as multi-emission, high brightness, and photostability. C-Dots have shown great potential in various fields, such as biosensing, nanomedicine, photo-catalysis, and bioimaging. This review focuses on the origin and synthesis of various C-Dots with special emphasis on bacterial detection, the antibacterial effect of C-Dots, and their mechanism.
引用
收藏
页码:4848 / 4860
页数:13
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