Human cardiomyocytes derived from iPS cells: Characterization and assessment of drug-induced changes on action potentials, ion currents, extracellular field potentials and impedance signals

被引：0

作者：

Kettenhofen, Ralf ^{[1
]}

Numann, Randy ^{[2
]}

Gibson, John Ken ^{[2
]}

Hebeisen, Simon ^{[3
]}

Duenbostell, Anika ^{[1
]}

Rubenchik, Olga ^{[1
]}

Tenelsen, Josef ^{[1
]}

Metzger, Peter ^{[1
]}

Bohlen, Heribert ^{[1
]}

机构：

[1] Axiogenesis AG, Cologne, Germany

[2] Ion Transport Assays Inc, St Louis, MO USA

[3] BSYS GmbH, Witterswil, Switzerland

来源：

JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS | 2014年 / 70卷 / 03期

关键词：

D O I：

10.1016/j.vascn.2014.03.152

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

0147

引用

页码：354 / 354

页数：1

共 26 条

[21] Assessment of extracellular field potential and Ca2+ transient signals for early QT/pro arrhythmia detection using human induced pluripotent stem cell-derived cardiomyocytes
Abi-Gerges, Najah
Pointon, Amy
Oldman, Karen L.
Brown, Martin R.
Pilling, Mark A.
Sefton, Clare E.
Garside, Helen
Pollard, Christopher E.
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 2017, 83 : 1 - 15
[22] CSAHi study: Validation of multi-electrode array systems (MEA60/2100) for prediction of drug-induced proarrhythmia using human iPS cell-derived cardiomyocytes -assessment of inter-facility and cells lot-to-lot-variability-
Nozaki, Yumiko
Honda, Yayoi
Watanabe, Hitoshi
Saiki, Shota
Koyabu, Kiyotaka
Itoh, Tetsuji
Nagasawa, Chiho
Nakamori, Chiaki
Nakayama, Chiaki
Iwasaki, Hiroshi
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Washio, Ikumi
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Miyamoto, Kaori
Yamanishi, Atsuhiro
Endo, Hiroko
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Kunimatsu, Takeshi
REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2016, 77 : 75 - 86
[23] CSAHi study: Usability assessment of multi-electrode array in combination with human iPS cell-derived cardiomyocytes for prediction of drug-induced QT prolongation and arrhythmia - Multi Channel Systems (MEA60 and MEA2100)
Kunimatsua, Takeshi
Nozaki, Yumiko
Honda, Yayoi
Watanabe, Hitoshi
Yamanishi, Atsuhiro
Nogawa, Hisashi
Endo, Hiroko
Saiki, Shota
Nagasawa, Chiho
Nakamori, Chiaki
Nakayama, Chiaki
Iwasaki, Hiroshi
Takahashi, Etsushi
Miyamoto, Kaori
Morimura, Kaoru
Tanaka, Kohji
Suzuki, Shinobu
Washio, Ikumi
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 2016, 81 : 385 - 385
[24] Optical Recording of Action Potentials in Human Induced Pluripotent Stem Cell-Derived Cardiac Single Cells and Monolayers Generated from Long QT Syndrome Type 1 Patients
Takaki, Tadashi
Inagaki, Azusa
Chonabayashi, Kazuhisa
Inoue, Keiji
Miki, Kenji
Ohno, Seiko
Makiyama, Takeru
Horie, Minoru
Yoshida, Yoshinori
STEM CELLS INTERNATIONAL, 2019, 2019
[25] CSAHi study-2: Validation of multi-electrode array systems (MEA60/2100) for prediction of drug-induced proarrhythmia using human iPS cell-derived cardiomyocytes: Assessment of reference compounds and comparison with non-clinical studies and clinical information
Nozaki, Yumiko
Honda, Yayoi
Watanabe, Hitoshi
Saiki, Shota
Koyabu, Kiyotaka
Itoh, Tetsuji
Nagasawa, Chiho
Nakamori, Chiaki
Nakayama, Chiaki
Iwasaki, Hiroshi
Suzuki, Shinobu
Tanaka, Kohji
Takahashi, Etsushi
Miyamoto, Kaori
Morimura, Kaoru
Yamanishi, Atsuhiro
Endo, Hiroko
Shinozaki, Junko
Nogawa, Hisashi
Shinozawa, Tadahiro
Saito, Fumiyo
Kunimatsu, Takeshi
REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2017, 88 : 238 - 251
[26] Optical Recording of Action Potentials in Human Induced Pluripotent Stem Cell-Derived Cardiac Single Cells and Monolayers Generated from Long QT Syndrome Type 1 Patients (vol 2019, 7532657, 2019)
Takaki, Tadashi
Inagaki, Azusa
Chonabayashi, Kazuhisa
Inoue, Keiji
Miki, Kenji
Ohno, Seiko
Makiyama, Takeru
Horie, Minoru
Yoshida, Yoshinori
STEM CELLS INTERNATIONAL, 2020, 2020

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