Human cardiomyocytes derived from iPS cells: Characterization and assessment of drug-induced changes on action potentials, ion currents, extracellular field potentials and impedance signals

被引：0

作者：

Kettenhofen, Ralf ^{[1
]}

Numann, Randy ^{[2
]}

Gibson, John Ken ^{[2
]}

Hebeisen, Simon ^{[3
]}

Duenbostell, Anika ^{[1
]}

Rubenchik, Olga ^{[1
]}

Tenelsen, Josef ^{[1
]}

Metzger, Peter ^{[1
]}

Bohlen, Heribert ^{[1
]}

机构：

[1] Axiogenesis AG, Cologne, Germany

[2] Ion Transport Assays Inc, St Louis, MO USA

[3] BSYS GmbH, Witterswil, Switzerland

来源：

JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS | 2014年 / 70卷 / 03期

关键词：

D O I：

10.1016/j.vascn.2014.03.152

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

0147

引用

页码：354 / 354

页数：1

共 26 条

[1] Human stem cell-derived cardiomyocytes detect drug-mediated changes in action potentials and ion currents
Gibson, John K.
Yue, Yimei
Bronson, Jared
Palmer, Cassie
Numann, Randy
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 2014, 70 (03) : 255 - 267
[2] Application of optical action potentials in human induced pluripotent stem cells-derived cardiomyocytes to predict drug-induced cardiac arrhythmias
Lu, H. R.
Hortigon-Vinagre, M. P.
Zamora, V.
Kopljar, I.
De Bondt, A.
Gallacher, D. J.
Smith, G.
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 2017, 87 : 53 - 67
[3] Effects of antidepressants on cardiac multiple ion channels and action potentials in human iPS cell-derived cardiomyocytes
Lee, Hyang-Ae
Kim, Ki-Suk
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 2019, 99
[4] Drug-induced torsadogenic risk assessment using human iPS cell-derived cardiomyocytes
Yamazaki, Daiju
Kitaguchi, Takashi
Ishimura, Masakazu
Taniguchi, Tomohiko
Yamanishi, Atsuhiro
Saji, Daisuke
Takahashi, Etsushi
Oguchi, Masao
Moriyama, Yuta
Maeda, Sanae
Miyamoto, Kaori
Morimura, Kaoru
Ohnaka, Hiroki
Tashibu, Hiroyuki
Sekino, Yuko
Miyamoto, Norimasa
Kanda, Yasunari
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 2018, 93 : 170 - 170
[5] Simultaneous measurement of action potentials and contractility of human iPS-derived cardiomyocytes for safety assessment of pharmaceutical compounds
Zhang, Xiaoyu
Ouyang, Wayne
Xi, Biao
Xu, Xiao
Wang, Xiaobo
Abassi, Yama A.
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 2015, 75 : 168 - 168
[6] Evaluation of nifedipine on action potentials, ion currents and calcium transients from adult human stem cell derived cardiomyocytes
Gibson, John Ken
Yue, Yimei
Bronson, Jared
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 2015, 75 : 195 - 195
[7] Assessment of drug-induced QT prolongation using human iPS cell-derived mature cardiomyocytes
Kanda, Yasunari
Li, Min
Ashihara, Takashi
Sekino, Yuko
Furukawa, Tetsushi
Kurokawa, Junko
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 2016, 81 : 384 - 384
[8] Discrimination power of optically recorded action potentials in cardiomyocytes derived from human induced pluripotent stem cells
Smith, Godfrey
Cooper, Jon
Hortigon-Vinagre, Maria
Ghouri, Iffath
Craig, Margaret-Ann
Anson, Blake
Wallis, Rob
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 2014, 70 (03) : 353 - 353
[9] A new paradigm for drug-induced torsadogenic risk assessment using human iPS cell-derived cardiomyocytes
Ando, Hiroyuki
Yoshinaga, Takashi
Yamamotoa, Wataru
Asakura, Keiichi
Uda, Takaaki
Taniguchi, Tomohiko
Ojima, Atsuko
Shinkyo, Raku
Kikuchi, Kiyomi
Osada, Tomoharu
Hayashi, Seiji
Kasai, Chieko
Miyamotoa, Norimasa
Tashibu, Hiroyuki
Yamazaki, Daiju
Sugiyama, Atsushi
Kanda, Yasunari
Sawada, Kohei
Sekino, Yuko
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 2017, 84 : 111 - 127
[10] Computational assessment of drug-induced effects on the electrocardiogram: from ion channel to body surface potentials
Zemzemi, Nejib
Bernabeu, Miguel O.
Saiz, Javier
Cooper, Jonathan
Pathmanathan, Pras
Mirams, Gary R.
Pitt-Francis, Joe
Rodriguez, Blanca
BRITISH JOURNAL OF PHARMACOLOGY, 2013, 168 (03) : 718 - 733

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