Cured meat consumption increases risk of readmission in COPD patients

被引:35
作者
de Batlle, Jordi [1 ,2 ]
Mendez, Michelle
Romieu, Isabelle [3 ]
Balcells, Eva [5 ]
Benet, Marta
Donaire-Gonzalez, David [1 ,4 ]
Ferrer, Jaume J. [5 ,6 ]
Orozco-Levi, Mauricio [2 ,5 ,7 ]
Anto, Josep M. [1 ,2 ]
Garcia-Aymerich, Judith [1 ]
机构
[1] Hosp Mar Res Inst IMIM, Ctr Res Environm Epidemiol CREAL, CIBERESP, Barcelona 08003, Spain
[2] UPF, Dept Expt & Hlth Sci, Barcelona, Spain
[3] Int Agcy Res Canc, Nutr & Metab Nutr Epidemiol Grp, F-69372 Lyon, France
[4] Ramon Llull Univ, Phys Act & Sports Sci Dept, Fundacio Blanquerna, Barcelona, Spain
[5] CIBER Enfermedades Resp CIBERES, Bunyola, Spain
[6] Hosp Gen Univ Vail dHebron, Serv Pneumol, Barcelona, Spain
[7] Fdn Cardiovasc Colombia, Serv Neumol, Bogota, Colombia
关键词
Chronic obstructive pulmonary disease; follow-up studies; hospitalisation; meat products; public health; OBSTRUCTIVE PULMONARY-DISEASE; DIETARY NITRATE; NITRIC-OXIDE; VALIDATION; ASTHMA;
D O I
10.1183/09031936.00116911
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Recent studies have shown that a high dietary intake of cured meat increases the risk of chronic obstructive pulmonary disease (COPD) development. However, its potential effects on COPD evolution have not been tested. We aimed to assess the association between dietary intake of cured meat and risk of COPD readmission in COPD patients. 274 COPD patients were recruited during their first COPD admission between 2004 and 2006, provided information on dietary intake of cured meat during the previous 2 yrs, and were followed until December 31, 2007 (median follow-up 2.6 yrs). Associations between cured meat intake and COPD admissions were assessed using parametric regression survival time models. Mean +/- SD age was 68 +/- 8 yrs, 93% of patients were male, 42% were current smokers, mean post-bronchodilator forced expiratory volume in 1 s (FEV1) was 53 +/- 16% predicted, and median cured meat intake was 23 g.day(-1). After adjusting for age, FEV1, and total caloric intake, high cured meat intake (more than median value) increased the risk of COPD readmission (adjusted HR 2.02, 95% CI 1.31-3.12; p=0.001). High cured meat consumption increases the risk of COPD readmission in COPD patients. The assessment of the effectiveness of healthy diet advice should be considered in the future.
引用
收藏
页码:555 / 560
页数:6
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