Bilateral acute retinal necrosis associated with neuroinfection in patient after renal transplantation

被引：4

作者：

Brydak-Godowska, Joanna ^{[1
]}

Szczepanik, Szymon ^{[1
,2
]}

Ciszek, Michal ^{[3
]}

Bialas, Dominika ^{[1
]}

Grzeszczyk, Miroslaw ^{[4
]}

Strzelecki, Dariusz ^{[5
]}

Kecik, Dariusz ^{[1
]}

机构：

[1] Med Univ Warsaw, Dept Ophthalmol, PL-02005 Warsaw, Poland

[2] Med Univ Warsaw, Chair & Dept Gen & Expt Pathol, PL-02005 Warsaw, Poland

[3] Med Univ Warsaw, Dept Immunol Transplantol & Internal Med, PL-02005 Warsaw, Poland

[4] Med Univ Warsaw, Dept Transplant Med & Nephrol, PL-02005 Warsaw, Poland

[5] Warsaw Hosp Infect Dis, Dept Infect Dis, Warsaw, Poland

来源：

MEDICAL SCIENCE MONITOR | 2011年 / 17卷 / 08期

关键词：

acute retinal necrosis; renal transplantation; immunosupression; neuroinfection; COMPLICATIONS;

D O I：

10.12659/MSM.881890

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Background: Acute retinal necrosis (ARN) is characterized by the triad of acute vitritis, peripheral necrotizing retinitis and vasculitis. Case Report: We report a case of 54-year-old woman with bilateral acute retinal necrosis associated with neuroinfection. Her past medical history included renal transplantation, hypertension and aortic stenosis. Observational case report: Diagnostic investigations included biochemical tests, lumbar puncture, eye ultrasonography and MRI of the brain. Anti-HSV IgG antibody titers were elevated in the blood and cerebrospinal fluid. In MRI T2-mode, inflammatory changes were found in the white matter of the right hemisphere. The patient was treated with systemic acyclovir, itraconazole, metronidazole and ciprofloxacin for 3 weeks. Retinal detachment was observed in both eyes. Conclusions: Acute retinal necrosis can be the single manifestation of herpes virus reactivation in patients after organ transplantation.

引用

页码：CS99 / CS102

页数：4

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