Psychiatric Symptoms in the Initial Motor Stage of Parkinson's Disease

被引：7

作者：

Stankovic, Iva ^{[1
]}

Stefanova, Elka ^{[1
,2
]}

Tomic, Aleksandra ^{[1
]}

Lukic, Milica Jecmenica ^{[1
]}

Stojkovic, Tanja ^{[1
]}

Markovic, Vladana ^{[1
]}

Stojmenovic, Gorana Mandic ^{[1
]}

Kresojevic, Nikola ^{[1
]}

Svetel, Marina ^{[1
,2
]}

Kostic, Vladimir ^{[1
,2
]}

机构：

[1] Clin Ctr Serbia, Neurol Clin, Belgrade, Serbia

[2] Univ Belgrade, Sch Med, Belgrade, Serbia

来源：

JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES | 2016年 / 28卷 / 03期

关键词：

SLEEP BEHAVIOR DISORDER; DE-NOVO; NEUROPSYCHIATRIC SYMPTOMS; NONMOTOR SYMPTOMS; RATING-SCALES; APATHY; DEPRESSION; INVENTORY; DEMENTIA; ANXIETY;

D O I：

10.1176/appi.neuropsych.15100244

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Neuropsychiatric symptoms (NPS) are common in Parkinson's disease (PD). The aim of this study was to estimate the correlates of NPS in patients with PD in the initial motor stage of the disease (hemiparkinsonism). A total of 111 patients with PD and 105 healthy control participants were assessed. Patients with PD experienced apathy, depression, and anxiety more frequently compared with healthy controls. Sleep disturbances occurred commonly in early PD patients. Patients with PD and mild cognitive impairment (MCI) had depression and anxiety more frequently, but not apathy, compared with patients with PD without MCI. The results of this study confirm a high burden of NPS even in the earliest motor stage of PD.

引用

页码：205 / 210

页数：6

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