In vitro Investigation of the Antimicrobial Activity of a Series of Lipophilic Phenols and Naphthols

被引：5

作者：

Govender, Thavendran ^{[1
]}

Govinden, Usha ^{[1
]}

Mocktar, Chunderika ^{[1
]}

Kruger, Hendrik G. ^{[1
]}

Veljkovic, Jelena ^{[2
]}

Cindro, Nikola ^{[2
]}

Bobinac, Damir ^{[2
]}

Zabcic, Ivana ^{[2
]}

Mlinaric-Majerski, Kata ^{[2
]}

Basaric, Nikola ^{[2
]}

机构：

[1] Univ KwaZulu Natal, Sch Hlth Sci, Catalysis & Peptide Res Unit, Durban, South Africa

[2] Rudjer Boskovic Inst, Dept Organ Chem & Biochem, Bijenicka Cesta 54, Zagreb 10000, Croatia

来源：

SOUTH AFRICAN JOURNAL OF CHEMISTRY-SUID-AFRIKAANSE TYDSKRIF VIR CHEMIE | 2016年 / 69卷

基金：

新加坡国家研究基金会;

关键词：

Antimicrobial activity; phenols; naphthols; quinone methides; PHENETHYL ALCOHOL; ESCHERICHIA-COLI; ANTIBACTERIAL ACTIVITY; QUINONE METHIDES; DERIVATIVES; PHOTODEHYDRATION; PERMEABILITY; CHEMISTRY; EXTRACTS; GROWTH;

D O I：

10.17159/0379-4350/2016/v69a6

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Five groups of phenols/naphthols (42 compounds in total) were synthesized and screened against Gram-positive Staphylococcus aureus and Bacillus subtilis, Gram-negative Escherichia coli and Klebsiella pneumoniae, and the fungus Candida albicans. Whereas compounds were found inactive against Gram-negative bacteria, potent activities against Gram-positive bacteria were observed. The activities correlate with the ability of molecules to form quinone methides, suggesting potential new modes of action.

引用

页码：44 / +

页数：11

共 50 条

[11] Biosynthesis of Silver nanoparticles and investigation of genotoxic effects and antimicrobial activity [J].

Nadaroglu, Hayrunnisa ;

Alayli, Azize ;

Ceker, Selcuk ;

Ogutcu, Hatice ;

Agar, Guleray .

INTERNATIONAL JOURNAL OF NANO DIMENSION, 2020, 11 (02) :158-167

[12] Investigation of the antimicrobial and anticancer activity of aminonaphthoquinones [J].

Wellington, Kevin W. ;

Kolesnikova, Natasha I. ;

Nyoka, Nomgqibelo B. P. ;

McGaw, Lyndy J. .

DRUG DEVELOPMENT RESEARCH, 2019, 80 (01) :138-146

[13] Phytochemical and in vitro antimicrobial and genotoxic activity in the brown algae Dictyopteris membranacea [J].

Akremi, N. ;

Cappoen, D. ;

Anthonissen, R. ;

Verschaeve, L. ;

Bouraoui, A. .

SOUTH AFRICAN JOURNAL OF BOTANY, 2017, 108 :308-314

[14] Total Content of Saponins, Phenols and Flavonoids and Antioxidant and Antimicrobial Activity of In Vitro Culture of Allochrusa gypsophiloides (Regel) Schischk Compared to Wild Plants [J].

Mursaliyeva, Valentina K. ;

Sarsenbek, Balaussa T. ;

Dzhakibaeva, Gulnara T. ;

Mukhanov, Tlek M. ;

Mammadov, Ramazan .

PLANTS-BASEL, 2023, 12 (20)

[15] IN VITRO ANTIMICROBIAL ACTIVITY SCREENING OF XYLARIA HYPOXYLON [J].

Canli, Kerem ;

Akata, Ilgaz ;

Altuner, Ergin Murat .

AFRICAN JOURNAL OF TRADITIONAL COMPLEMENTARY AND ALTERNATIVE MEDICINES, 2016, 13 (04) :42-46

[16] Alkylated chitosan nanomaterials for enhanced antimicrobial activity and delivery of fusidic acid: Preparation and preliminary in vitro investigation [J].

Bostanudin, Mohammad F. ;

Salam, Aisha ;

Kayed, Kawthar ;

Jan, Nasrullah .

JOURNAL OF APPLIED POLYMER SCIENCE, 2023, 140 (26)

[17] Antimicrobial and Antioxidant Activity of the Biologically Synthesized Tellurium Nanorods; A Preliminary In vitro Study [J].

Shakibaie, Mojtaba ;

Adeli-Sardou, Mahboubeh ;

Mohammadi-Khorsand, Tayebe ;

Zeydabadi-Nejad, Mahdie ;

Amirafzali, Ehsan ;

Amirpour-Rostami, Sahar ;

Ameri, Atefeh ;

Forootanfar, Hamid .

IRANIAN JOURNAL OF BIOTECHNOLOGY, 2017, 15 (04) :268-276

[18] Chemical composition of fixed oil and in vitro antimicrobial activity of Andrographis paniculata root [J].

Farhana, Sharika ;

Aziz, Shahin ;

Rahman, Sharjana ;

Afrin, Sadia ;

Bhuiyan, Mohammad Nazrul Islam ;

Al-Reza, Sharif Md .

JOURNAL OF KING SAUD UNIVERSITY SCIENCE, 2022, 34 (04)

[19] Synthesis and investigation of antimicrobial and antioxidant activity of anthraquinonylhydrazones [J].

Stasevych, Maryna ;

Zvarych, Viktor ;

Lunin, Volodymyr ;

Kopak, Nazarii ;

Komarovska-Porokhnyavets, Olena ;

Deniz, Nahide Gulsah ;

Sayil, Cigdem ;

Ozyurek, Mustafa ;

Guclu, Kubilay ;

Vovk, Mykhailo ;

Novikov, Volodymyr .

MONATSHEFTE FUR CHEMIE, 2018, 149 (06) :1111-1119

[20] Investigation of in vivo radioprotective and in vitro antioxidant and antimicrobial activity of garlic (Allium Sativum) [J].

Batcioglu, K. ;

Yilmaz, Z. ;

Satilmis, B. ;

Uyumlu, A. B. ;

Erkal, H. S. ;

Yucel, N. ;

Gunal, S. ;

Serin, M. ;

Demirtas, H. .

EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 2012, 16 :47-57

← 1 2 3 4 5 →