Application of Sulfur Ylides in 1,2-Difunctionalization of Arynes via Insertion into a C-S σ-Bond

被引：28

作者：

Ahire, Milind M. ^{[1
,2
]}

Thoke, Mahesh B. ^{[1
]}

Mhaske, Santosh B. ^{[1
,2
]}

机构：

[1] Natl Chem Lab, CSIR, Div Organ Chem, Pune 411008, Maharashtra, India

[2] Natl Chem Lab, CSIR, Acad Sci & Innovat Res AcSIR, Pune 411008, Maharashtra, India

来源：

ORGANIC LETTERS | 2018年 / 20卷 / 03期

关键词：

4+1 ANNULATION; CARBON-CARBON; ACCESS; ARYLATION; CYCLOPROPANATION; HETEROCYCLES; OLEFINATION; EPOXIDATION; SULFOXIDES; CATALYSIS;

D O I：

10.1021/acs.orglett.7b04003

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel reactivity of sulfur ylides has been demonstrated in a transition-metal-free protocol to access ortho-substituted thioanisole derivatives by insertion of arynes into a C-S sigma-bond in moderate to good yields. The reaction involves the formation of C-C and C-S bonds and consecutive breaking of two C-S bonds under operationally mild reaction conditions.

引用

页码：848 / 851

页数：4

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