DNA microarrays on silicon surfaces through thiol-ene chemistry

被引:43
作者
Escorihuela, Jorge [1 ]
Jose Banuls, Maria [1 ]
Puchades, Rosa [1 ]
Maquieira, Angel [1 ]
机构
[1] Univ Politecn Valencia, Ctr Reconocimiento Mol & Desarrollo Tecnol, Dept Quim, Valencia 46022, Spain
关键词
PHARMACOGENOMICS; TECHNOLOGIES; MONOLAYERS; TOOLS;
D O I
10.1039/c2cc17321b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The potential of thiol-ene chemistry as a selective strategy to functionalize silicon materials for DNA microarraying is demonstrated and applied to discriminate genetic variations.
引用
收藏
页码:2116 / 2118
页数:3
相关论文
共 27 条
[1]   Selective chemical modification of silicon nitride/silicon oxide nanostructures to develop label-free biosensors [J].
Banuls, Maria-Jose ;
Gonzalez-Pedro, Victoria ;
Barrios, Carlos A. ;
Puchades, Rosa ;
Maquieira, Angel .
BIOSENSORS & BIOELECTRONICS, 2010, 25 (06) :1460-1466
[2]   Functional monolayers on oxide-free silicon surfaces via thiol-ene click chemistry [J].
Campos, Mabel A. Caipa ;
Paulusse, Jos M. J. ;
Zuilhof, Han .
CHEMICAL COMMUNICATIONS, 2010, 46 (30) :5512-5514
[3]   Bioorthogonal Chemistry for Site-Specific Labeling and Surface Immobilization of Proteins [J].
Chen, Yong-Xiang ;
Triola, Gemma ;
Waldmann, Herbert .
ACCOUNTS OF CHEMICAL RESEARCH, 2011, 44 (09) :762-773
[4]   The Emergence of Thiol-Ene Coupling as a Click Process for Materials and Bioorganic Chemistry [J].
Dondoni, Alessandro .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2008, 47 (47) :8995-8997
[5]   Multi-technique comparison of immobilized and hybridized oligonucleotide surface density on commercial amine-reactive microarray slides [J].
Gong, P ;
Harbers, GM ;
Grainger, DW .
ANALYTICAL CHEMISTRY, 2006, 78 (07) :2342-2351
[6]   Facile DNA Immobilization on Surfaces through a Catecholamine Polymer [J].
Ham, Hyun Ok ;
Liu, Zhongqiang ;
Lau, K. H. Aaron ;
Lee, Haeshin ;
Messersmith, Phillip B. .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2011, 50 (03) :732-736
[7]   Carbohydrate arrays as tools for research and diagnostics [J].
Horlacher, Tim ;
Seeberger, Peter H. .
CHEMICAL SOCIETY REVIEWS, 2008, 37 (07) :1414-1422
[8]   Thiol-Ene Click Chemistry [J].
Hoyle, Charles E. ;
Bowman, Christopher N. .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, 49 (09) :1540-1573
[9]   Surface plasmon resonance imaging measurements of DNA hybridization adsorption and streptavidin/DNA multilayer formation at chemically modified gold surfaces [J].
Jordan, CE ;
Frutos, AG ;
Thiel, AJ ;
Corn, RM .
ANALYTICAL CHEMISTRY, 1997, 69 (24) :4939-4947
[10]   Patterning and visualizing self-assembled monolayers with low-energy electrons [J].
Krupke, R ;
Malik, S ;
Weber, HB ;
Hampe, O ;
Kappes, MM ;
von Löhneysen, H .
NANO LETTERS, 2002, 2 (10) :1161-1164