Simple approach to the development of a CCC solvent selection protocol suitable for automation

被引：58

作者：

Garrard, IJ ^{[1
]}

机构：

[1] Brunel Univ, Brunel Inst Bioengn, Uxbridge UB8 3PH, Middx, England

来源：

JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES | 2005年 / 28卷 / 12-13期

关键词：

countercurrent chromatography; CCC; solvent selection;

D O I：

10.1081/JLC-200063571

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

One of the biggest problems with countercurrent chromatography, when it comes to its practical application in an industrial environment, is developing a protocol and corresponding solvent system for its operation. This paper critically reviews previous proposals for solvent selection and suggests a scheme that is suitable for use by an inexperienced user and for automation using a modern liquid handling robot.

引用

页码：1923 / 1935

页数：13

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