Management of osteoporosis in patients hospitalized for hip fractures

被引:33
作者
Ip, T. P. [1 ,2 ]
Leung, J. [3 ]
Kung, A. W. C. [1 ]
机构
[1] Univ Hong Kong, Queen Mary Hosp, Dept Med, Hong Kong, Hong Kong, Peoples R China
[2] Tung Wah Eastern Hosp, Dept Med, Hong Kong, Hong Kong, Peoples R China
[3] Ruttonjee Hosp, Dept Med, Hong Kong, Hong Kong, Peoples R China
关键词
Osteoporosis; VITAMIN-D SUPPLEMENTATION; INTESTINAL CALCIUM-ABSORPTION; SERUM 25-HYDROXYVITAMIN D; BONE-MINERAL DENSITY; POSTMENOPAUSAL WOMEN; PARATHYROID-HORMONE; NONVERTEBRAL FRACTURES; ZOLEDRONIC ACID; DOUBLE-BLIND; MUSCLE STRENGTH;
D O I
10.1007/s00198-010-1398-8
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Hip fracture is associated with high morbidity, mortality, and economic burden worldwide. It is also a major risk factor for a subsequent fracture. A literature search on the management of osteoporosis in patients with hip fracture was performed on the Medline database. Only one clinical drug trial was conducted in patients with a recent hip fracture. Further studies that specifically address post-fracture management of hip fracture are needed. The efficacy of anti-osteoporosis medication in older individuals and those at high risk of fall is reviewed in this paper. Adequate nutrition is vital for bone health and to prevent falls, especially in malnourished patients. Protein, calcium, and vitamin D supplementation is associated with increased hip BMD and a reduction in falls. Fall prevention, exercise, and balance training incorporated in a comprehensive rehabilitation program are essential to improve functional disability and survival. Exclusion of secondary causes of osteoporosis and treatment of coexistent medical conditions are also vital. Such a multidisciplinary team approach to the management of hip fracture patients is associated with a better clinical outcome. Although hip fracture is the most serious of all fractures, osteoporosis management should be prioritized to prevent deterioration of health and occurrence of further fracture.
引用
收藏
页码:S605 / S614
页数:10
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