Physical resilience in older adults: Potential use in promoting healthy aging

被引：11
作者：
Li, Jiatong [1 ]
Chhetri, Jagadish K. [1 ]
Ma, Lina [1 ]
机构：
[1] Capital Med Univ, Xuanwu Hosp, Natl Clin Res Ctr Geriatr Dis, Dept Geriatr, Beijing 100053, Peoples R China
来源：
AGEING RESEARCH REVIEWS | 2022年 / 81卷
基金：
北京市自然科学基金;
关键词：
Physical resilience; Healthy aging; Older adults; Frailty; Intrinsic capacity; EXERCISE; FRAILTY; MICE;
D O I：
10.1016/j.arr.2022.101701
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Physical resilience is a dynamic concept referring to the physiological response when the body is exposed to stressors. The level of physical resilience is the sum of underlying physiological reserves. Moreover, it may not only be determined by age, genetics, or exposure to a variety of diseases, but is also closely related to the psychological, social, and environmental factors of an individual. This paper summarizes our present under-standing of the relationship between physical resilience and other concepts closely related to it. Furthermore, we illustrate the current research progress on physical resilience models and clinical resilience assessment. Besides, this paper intends to present a better understanding of physical resilience and its use in treatment decision -making, personalized diagnosis and disease management, and prevention and rehabilitation strategies.
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