The human amniotic epithelial cells (ECHA) as a possible source of stem cells (CT)

被引：0

作者：

Garcia-Lopez, Guadalupe ^{[1
]}

Lydia Garcia-Castro, Irma ^{[1
]}

Avila-Gonzalez, Daniela ^{[1
]}

Molina-Hernandez, Anayansi ^{[1
]}

Flores-Herrera, Hector ^{[2
]}

Merchant-Larios, Horacio ^{[3
]}

Diaz-Martinez, Fabian ^{[1
]}

机构：

[1] Inst Nacl Perinatol Isidro Espinosa de los Reyes, Dept Biol Celular, Mexico City, DF, Mexico

[2] Inst Nacl Perinatol Isidro Espinosa de los Reyes, Dept Bioquim & Biol Celular, Mexico City, DF, Mexico

[3] Univ Nacl Autonoma Mexico, Inst Invest Biomed, Dept Biol Celular & Fisiol, Mexico City 04510, DF, Mexico

来源：

GACETA MEDICA DE MEXICO | 2015年 / 151卷 / 01期

关键词：

Stem cell; Human fetal membrane; Human amniotic epithelial cell; OSTEOGENIC DIFFERENTIATION; EPIGENETIC REGULATION; ADIPOSE-TISSUE; HUMAN PLACENTA; BONE-MARROW; TRANSPLANTATION; PLURIPOTENCY; MEMBRANE; EXPRESSION; CULTURE;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

There have been major recent advances in the field of developmental biology due to the investigation on stem cells (SC). Stem cells are characterized by their capacity of auto-renewal and differentiation to different cellular phenotypes. Based on the developmental stage, they can be classified into two different types: embryonic SCs and adult SCs. It has been widely reported that several problems need to be resolved before their possible clinical applications. As a result, fetal membranes have been suggested as an alternative source of SCs. In the human amniotic epithelium, the presence of markers of pluripotent SC's has been reported, and its capacity as a feeder layer for expansion of different SC types. Also, fetal membranes are a discarded product after delivery, and thus there are not any ethical issues related to its use. In conclusion, the human amniotic epithelium can be a strong candidate for regenerative medicine.

引用

页码：76 / 84

页数：9

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