ONE-POT THREE-COMPONENT SYNTHESIS OF 4-ARYL-3,4-DIHYDRO-PYRIMIDIN-2(1H)-THIONES CATALYZED BY Ni LOADED SiO2

被引：10

作者：

Maddila, Suresh ^{[1
]}

Jonnalagadda, Sreekanth B. ^{[1
]}

机构：

[1] Univ KwaZulu Natal, Sch Chem, ZA-4000 Durban, South Africa

来源：

BULLETIN OF THE CHEMICAL SOCIETY OF ETHIOPIA | 2012年 / 26卷 / 01期

关键词：

Ni loaded SiO2; 4-Aryl-3,4-dihydropyrimidin-2(1H)-thiones; One-pot three-component synthesis; Methyl; 3-oxopentanoate; Aldehydes; Thiourea; SOLVENT-FREE CONDITIONS; BIGINELLI REACTION; SILICA; IRRADIATION; OXIDATION; SYSTEM;

D O I：

10.4314/bcse.v26i1.13

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A simple and efficient method has been developed for the synthesis of 4-aryl-3,4-dihydropyrimidin-2(1H)-thiones from methyl 3-oxopentanoate, aldehydes and thiourea in the presence of a catalytic amount of Ni loaded SiO2 at room temperature.

引用

页码：121 / 126

页数：6

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