Hydrogen peroxide-mediated killing of Caenorhabditis elegans:: a common feature of different streptococcal species

被引：40
作者：
Bolm, M
Jansen, WTM
Schnabel, R
Chhatwal, GS
机构：
[1] GBF, Dept Microbial Pathogenesis & Vaccine Res, German Res Ctr Biotechnol, D-38124 Braunschweig, Germany
[2] Univ Utrecht, Med Ctr, NL-3584 CX Utrecht, Netherlands
[3] Tech Univ Braunschweig, Genet Inst, D-38106 Braunschweig, Germany
来源：
INFECTION AND IMMUNITY | 2004年 / 72卷 / 02期
关键词：
D O I：
10.1128/IAI.72.2.1192-1194.2004
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Recently, we reported that Streptococcus pyogenes kills Caenorhabditis elegans by the use of hydrogen peroxide (H2O2). Here we show that diverse streptococcal species cause death of C elegans larvae in proportion to the level of H2O2 produced. H2O2 may mask the effects of other pathogenicity factors of catalase-negative bacteria in the C. elegans infection model.
引用
收藏
页码：1192 / 1194
页数：3
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