Allogeneic hematopoietic stem cell transplantation using a reduced-intensity conditioning regimen in infants: Experience at a single institution in Mexico

被引：8
作者：
Gonzalez Llano, Oscar [1 ]
Jaime Perez, Jose Carlos
Cantu Rodriguez, Olga
Mancias Guerra, Consuelo
Gutierrez Aguirre, Homero
Herrera Garza, Jose Luis
Rodriguez-Romo, Laura
Gomez Almaguer, David
机构：
[1] Univ Autonoma Nuevo Leon, Univ Hosp, Monterrey 64460, Nuevo Leon, Mexico
来源：
PEDIATRIC HEMATOLOGY AND ONCOLOGY | 2008年 / 25卷 / 01期
关键词：
allogeneic stem cell transplantation; infants; reduced-intensity conditioning regimen;
D O I：
10.1080/08880010701773621
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The authors report their experience with allogeneic hematopoietic stem cell transplantation in infants at a university hospital in Mexico. Five infants had one of each of the following diagnoses: acute lymphoblastic leukemia, osteopetrosis for which the patient underwent 2 procedures, acute disseminated multiorgan Langerhans cell histiocytosis, and two cases of hemophagocytic lymphohistiocytosis. The source of stem cells for grafting in 2 children was peripheral blood, and in 3 children was unrelated cord blood. A reduced-intensity conditioning regimen including fludarabine, cyclophosphamide, and melphalan was administrated. Three patients are disease-free transplant survivors without graft-versus-host disease after 46, 34, and 16 months.
引用
收藏
页码：39 / 47
页数：9
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