Prediction and Survival Analysis of Patients After Liver Transplantation Using RBF Networks

被引:3
作者
Raji, C. G. [1 ]
Chandra, S. S. Vinod [2 ]
机构
[1] Manonmaniam Sundaranar Univ, Dept Comp Sci & Engn, Tirunelveli, Tamil Nadu, India
[2] Univ Kerala, Ctr Comp, Thiruvananthapuram, Kerala, India
来源
DATA MINING AND BIG DATA, DMBD 2016 | 2016年 / 9714卷
关键词
Liver transplantation; Survival prediction; Radial Basis; Function network; Artificial Neural Networks; Survival analysis; NEURAL-NETWORKS; OUTCOMES;
D O I
10.1007/978-3-319-40973-3_14
中图分类号
TP18 [人工智能理论];
学科分类号
081104 ; 0812 ; 0835 ; 1405 ;
摘要
Prognostic models are becoming useful in assessing the severity of illness and survival analysis in medical domain. Based on the studies, we realized that the current models used in liver transplantation prognosis seems to be less accurate. In this paper, we propose a highly improved model for predicting three month post liver transplantation survival. We performed experiments on the United Nations Organ Sharing dataset, with a 10-fold cross-validation. An accuracy of 86.95% was observed when Radial Basis Function Artificial Neural Network model was used. Other similar methods were compared with the proposed one based on the prediction accuracy. A survival analysis study for a span of 13 years was also done by comparing with MELD an actual dataset. The reported results indicate that the proposed model is suitable for long term survival analysis after liver transplantation.
引用
收藏
页码:147 / 155
页数:9
相关论文
共 15 条
[1]   MTar: a computational microRNA target prediction architecture for human transcriptome [J].
Chandra, Vinod ;
Girijadevi, Reshmi ;
Nair, Achuthsankar S. ;
Pillai, Sreenadhan S. ;
Pillai, Radhakrishna M. .
BMC BIOINFORMATICS, 2010, 11
[2]   Predicting patient survival after liver transplantation using evolutionary multi-objective artificial neural networks [J].
Cruz-Ramirez, Manuel ;
Hervas-Martinez, Cesar ;
Carlos Fernandez, Juan ;
Briceno, Javier ;
de la Mata, Manuel .
ARTIFICIAL INTELLIGENCE IN MEDICINE, 2013, 58 (01) :37-49
[3]   PREDICTING OUTCOMES AFTER LIVER-TRANSPLANTATION - A CONNECTIONIST APPROACH [J].
DOYLE, HR ;
DVORCHIK, I ;
MITCHELL, S ;
MARINO, IR ;
EBERT, FH ;
MCMICHAEL, J ;
FUNG, JJ .
ANNALS OF SURGERY, 1994, 219 (04) :408-415
[4]   EARLY DEATH OR RETRANSPLANTATION IN ADULTS AFTER ORTHOTOPIC LIVER-TRANSPLANTATION - CAN OUTCOME BE PREDICTED [J].
DOYLE, HR ;
MARINO, IR ;
JABBOUR, N ;
ZETTI, G ;
MCMICHAEL, J ;
MITCHELL, S ;
FUNG, J ;
STARZL, TE .
TRANSPLANTATION, 1994, 57 (07) :1028-1036
[5]  
Hareendran A., 2014, ARTIFICIAL INTELLIGE
[6]   A model to predict survival in patients with end-stage liver disease [J].
Kamath, PS ;
Wiesner, RH ;
Malinchoc, M ;
Kremers, W ;
Therneau, TM ;
Kosberg, CL ;
D'Amico, G ;
Dickson, ER ;
Kim, WR .
HEPATOLOGY, 2001, 33 (02) :464-470
[7]   Five Years Survival of Patients After Liver Transplantation and Its Effective Factors by Neural Network and Cox Poroportional Hazard Regression Models [J].
Khosravi, Bahareh ;
Pourahmad, Saeedeh ;
Bahreini, Amin ;
Nikeghbalian, Saman ;
Mehrdad, Goli .
HEPATITIS MONTHLY, 2015, 15 (09)
[8]   The prediction of risk of recurrence and time to recurrence of hepatocellular carcinoma after orthotopic liver transplantation: A pilot study [J].
Marsh, JW ;
Dvorchik, I ;
Subotin, M ;
Balan, V ;
Rakela, J ;
Popechitelev, EP ;
Subbotin, V ;
Casavilla, A ;
Carr, BI ;
Fung, JJ ;
Iwatsuki, S .
HEPATOLOGY, 1997, 26 (02) :444-450
[9]  
Parmanto B, 2001, METHOD INFORM MED, V40, P386
[10]   International normalized ratios (INR): the first 20 years [J].
Poller, L .
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2004, 2 (06) :849-860