Impact of wastewater from different sources on the prevalence of antimicrobial-resistant Escherichia coli in sewage treatment plants in South India

被引：61

作者：

Akiba, Masato ^{[1
,2
]}

Senba, Hironobu ^{[3
]}

Otagiri, Haruna ^{[4
]}

Prabhasankar, Valipparambil P. ^{[5
]}

Taniyasu, Sachi ^{[6
]}

Yamashita, Nobuyoshi ^{[6
]}

Lee, Ken-ichi ^{[1
]}

Yamamoto, Takehisa ^{[7
]}

Tsutsui, Toshiyuki ^{[7
]}

Joshua, Derrick Ian ^{[5
]}

Balakrishna, Keshava ^{[5
]}

Bairy, Indira ^{[8
]}

Iwata, Taketoshi ^{[1
]}

Kusumoto, Masahiro ^{[1
]}

Kannan, Kurunthachalam ^{[9
,10
]}

Guruge, Keerthi S. ^{[11
]}

机构：

[1] Natl Agr & Food Res Org, Natl Inst Anim Hlth, Bacterial & Parasit Dis Res Div, Tsukuba, Ibaraki 3050856, Japan

[2] Osaka Prefecture Univ, Grad Sch Life & Environm Sci, Izumisano, Osaka, Japan

[3] Anim Quarantine Serv, Quarantine Dept, Anim Inspect Div, Yokohama, Kanagawa, Japan

[4] Tobu Livestock Hyg Serv Ctr, Fuefuki, Yamanashi, Japan

[5] Manipal Univ, Manipal Inst Technol, Dept Civil Engn, Manipal, Karnataka, India

[6] Natl Inst Adv Ind Sci & Technol, Tsukuba, Ibaraki, Japan

[7] Natl Agr & Food Res Org, Natl Inst Anim Hlth, Viral Dis & Epidemiol Res Div, Tsukuba, Ibaraki 3050856, Japan

[8] Manipal Univ, Dept Microbiol, Melaka Manipal Med Coll, Manipal, Karnataka, India

[9] SUNY Albany, Wadsworth Ctr, New York State Dept Hlth, Albany, NY 12222 USA

[10] SUNY Albany, Dept Environm Hlth Sci, Albany, NY 12222 USA

[11] Natl Agr & Food Res Org, Natl Inst Anim Hlth, Pathol & Pathophysiol Res Div, Tsukuba, Ibaraki 3050856, Japan

来源：

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY | 2015年 / 115卷

基金：

日本学术振兴会;

关键词：

Hospital effluent; Sewage treatment plant; India; Environmental contamination; Antimicrobial resistance; E coli; IN-HOSPITAL WASTEWATERS; ANTIBIOTIC-RESISTANCE; BACTERIA; MUNICIPAL;

D O I：

10.1016/j.ecoenv.2015.02.018

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The sewage treatment plant (STP) is one of the most important interfaces between the human population and the aquatic environment, leading to contamination of the latter by antimicrobial-resistant bacteria. To identify factors affecting the prevalence of antimicrobial-resistant bacteria, water samples were collected from three different STPs in South India. STP1 exclusively treats sewage generated by a domestic population. STP2 predominantly treats sewage generated by a domestic population with a mix of hospital effluent. STP3 treats effluents generated exclusively by a hospital. The water samples were collected between three intermediate treatment steps including equalization, aeration, and clarification, in addition to the outlet to assess the removal rates of bacteria as the effluent passed through the treatment plant. The samples were collected in three different seasons to study the effect of seasonal variation. Escherichia coli isolated from the water samples were tested for susceptibility to 12 antimicrobials. The results of logistic regression analysis suggest that the hospital wastewater inflow significantly increased the prevalence of antimicrobial-resistant E. coli, whereas the treatment processes and sampling seasons did not affect the prevalence of these isolates. A bias in the genotype distribution of E. coli was observed among the isolates obtained from STP3. In conclusion, hospital wastewaters should be carefully treated to prevent the contamination of Indian environment with antimicrobial-resistant bacteria. (C) 2015 Elsevier Inc. All rights reserved.

引用

页码：203 / 208

页数：6

共 23 条

[1] Effects of a Realistic Mixture of Antibiotics on Resistant and Nonresistant Sewage Sludge Bacteria in Laboratory-Scale Treatment Plants [J].