The alpha-chemokine, stromal cell-derived factor-1α (SDF-1α), binds to the transmembrane G-protein coupled CXCR-4 receptor and activates multiple signal transduction pathways.

被引:0
|
作者
Ganju, RK
Brubaker, SA
Meyer, J
Dutt, P
Yang, Y
Qin, S
Newman, W
Groopman, JE
机构
[1] Harvard Inst Med, Beth Israel Deaconess Med Ctr, Div Expt Med, Boston, MA USA
[2] LeukoSite Inc, Cambridge, MA USA
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
248
引用
收藏
页码:62A / 62A
页数:1
相关论文
共 50 条
  • [1] The α-chemokine, stromal cell-derived factor-1α, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways
    Ganju, RK
    Brubaker, SA
    Meyer, J
    Dutt, P
    Yang, YM
    Qin, SX
    Newman, W
    Groopman, JE
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (36) : 23169 - 23175
  • [2] The role of the chemokine receptor CXCR-4 and stromal cell-derived factor-1 (SDF-1) in trans-endothelial chemotaxis and marrow homing of hematopoietic stem cells.
    Jo, DY
    Rafii, S
    Hamada, Y
    Moore, MAS
    BLOOD, 1998, 92 (10) : 56A - 56A
  • [3] Recognition of a CXCR4 sulfotyrosine by the chemokine stromal cell-derived factor-1α (SDF-1α/CXCL12)
    Veldkamp, Christopher T.
    Seibert, Christoph
    Peterson, Francis C.
    Sakmar, Thomas P.
    Volkman, Brian F.
    JOURNAL OF MOLECULAR BIOLOGY, 2006, 359 (05) : 1400 - 1409
  • [4] Expression and function of the stromal cell-derived factor-1 (SDF-1) and CXC chemokine receptor 4 (CXCR4) in the swine ovarian follicle
    Basini, G.
    Ragionieri, L.
    Bussolati, S.
    Di Lecce, R.
    Cacchioli, A.
    Dettin, M.
    Cantoni, A. M.
    Grolli, S.
    La Bella, O.
    Zamuner, A.
    Grasselli, F.
    DOMESTIC ANIMAL ENDOCRINOLOGY, 2020, 71
  • [5] The chemokine SDF-1, stromal cell-derived factor 1, attracts early stage B cell precursors via the chemokine receptor CXCR4
    DApuzzo, M
    Rolink, A
    Loetscher, M
    Hoxie, JA
    ClarkLewis, I
    Melchers, F
    Baggiolini, M
    Moser, B
    EUROPEAN JOURNAL OF IMMUNOLOGY, 1997, 27 (07) : 1788 - 1793
  • [6] Expression of stromal derived factor-1 (SDF-1) and chemokine receptor (CXCR4) in bone metastasis of renal carcinoma
    Fu-long Zhao
    Wei Guo
    Molecular Biology Reports, 2011, 38 : 1039 - 1045
  • [7] Expression of stromal derived factor-1 (SDF-1) and chemokine receptor (CXCR4) in bone metastasis of renal carcinoma
    Zhao, Fu-long
    Guo, Wei
    MOLECULAR BIOLOGY REPORTS, 2011, 38 (02) : 1039 - 1045
  • [8] Immunohistochemical expression of stromal cell-derived factor-1 (SDF-1) and CXCR4 ligand receptor system in hepatocellular carcinoma
    Li, W.
    Gomez, E.
    Zhang, Z.
    JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2007, 26 (04): : 527 - 533
  • [9] Overexpression of the chemokine receptor CXCR4 in B cell chronic lymphocytic leukemia is associated with increased functional response to stromal cell-derived factor-1 (SDF-1)
    R Möhle
    C Failenschmid
    F Bautz
    L Kanz
    Leukemia, 1999, 13 : 1954 - 1959
  • [10] Overexpression of the chemokine receptor CXCR4 in B cell chronic lymphocytic leukemia is associated with increased functional response to stromal cell-derived factor-1 (SDF-1)
    Möhle, R
    Failenschmid, C
    Bautz, F
    Kanz, L
    LEUKEMIA, 1999, 13 (12) : 1954 - 1959