The Design of RNA Biosensor Based on Nano-gold and Magnetic Nano-particle

被引:0
|
作者
Yang, Jing [1 ]
Yin, Zhi-xiang [1 ]
Cui, Jian-zhong [2 ]
Huang, Kai-feng [3 ]
机构
[1] Anhui Univ Sci & Technol, Sch Math & Big Data, Huainan, Peoples R China
[2] Anhui Univ Sci & Technol, Sch Elect & Informat Engn, Huainan, Peoples R China
[3] Huainan Normal Univ, Sch Mech & Elect Engn, Huainan, Peoples R China
基金
中国国家自然科学基金;
关键词
RNA biosensor; magnetic nano-particle; gold nano-particle; environmental monitoring; POLYNUCLEOTIDES; IMMOBILIZATION; NANOPARTICLES; BEACON; AU;
D O I
10.3233/FI-2019-1768
中图分类号
TP31 [计算机软件];
学科分类号
081202 ; 0835 ;
摘要
Detecting the quality of drinking water is very important in researching the current status and predicting trends of variation, as well as fundamentally solving the water pollution problem. Recently, the application and development of biosensor provide a powerful analytical tool for detecting pollutants of drinking water, but high selectivity, specificity, short response time, and low cost are particularly desired in the detection process. In this paper, RNA molecules in combination with nano-gold and magnetic nano-particles were proposed as design strategies of the biosensor. The proposed designs have distinct advantages over conventional biosensor in the following aspects: the high affinity capacity, sensitivity, and practicability. Our work provided an alternative method to monitor the environment of drinking water, and may find applications in various monitoring fields.
引用
收藏
页码:289 / 298
页数:10
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