Association of the careggi collateral score with radiological outcomes after thrombectomy for stroke with an occlusion of the middle cerebral artery

被引：5

作者：

Cappellari, Manuel ^{[1
]}

Saia, Valentina ^{[2
]}

Pracucci, Giovanni ^{[3
]}

Fainardi, Enrico ^{[4
]}

Nencini, Patrizia ^{[5
]}

Malfatto, Laura ^{[6
]}

Tassi, Rossana ^{[7
]}

Cerrato, Paolo ^{[8
]}

Mancuso, Michelangelo ^{[9
]}

Pesare, Angela ^{[10
]}

La Spina, Paolino ^{[11
]}

Lotti, Enrico Maria ^{[12
]}

Casalena, Alfonsina ^{[13
]}

Petruzzellis, Marco ^{[14
]}

Baracchini, Claudio ^{[15
,16
]}

Via, Alessandra Giai ^{[17
]}

Gaudiano, Carmen ^{[18
]}

Sallustio, Fabrizio ^{[19
]}

Tassinari, Tiziana ^{[2
]}

Critelli, Adriana ^{[20
]}

Melis, Maurizio ^{[21
]}

Persico, Alessandra ^{[22
]}

Casetta, Ilaria ^{[23
]}

Sacco, Simona ^{[24
]}

Ferrandi, Delfina ^{[25
]}

Marcheselli, Simona ^{[26
]}

Russo, Monia ^{[27
]}

Zivelonghi, Cecilia ^{[1
]}

Mandruzzato, Nicolo ^{[28
]}

Invernizzi, Paolo ^{[29
]}

Romano, Daniele ^{[30
]}

Nicolini, Ettore ^{[31
]}

Scoditti, Umberto ^{[32
]}

Magoni, Mauro ^{[33
]}

Cariddi, Lucia Princiotta ^{[34
]}

Vallone, Stefano ^{[35
]}

Inzitari, Domenico ^{[3
]}

Toni, Danilo ^{[31
]}

Mangiafico, Salavatore ^{[36
]}

机构：

[1] Azienda Osped Univ Integrata, Stroke Unit, DAI Neurosci, Piazzale A Stefani 1, I-37126 Verona, Italy

[2] S Corona Hosp, Neurol & Stroke Unit, Pietra Ligure, Italy

[3] Univ Florence, Dept NEUROFARBA, Neurosci Sect, Florence, Italy

[4] Univ Firenze, Osped Univ Careggi, Dipartimento Sci Biomed Sperimentali & Clin, Neuroradiol, Florence, Italy

[5] Careggi Univ Hosp, Stroke Unit, Florence, Italy

[6] IRCCS Osped Policlin San Martino, Neurol & Stroke Unit, Genoa, Italy

[7] Univ Hosp Siena, Stroke Unit, Siena, Italy

[8] Citta Salute & Sci Molinette, Stroke Unit, Turin, Italy

[9] Univ Pisa, Neurol Inst, Dept Clin & Expt Med, Pisa, Italy

[10] SS Annunziata Hosp, SC Neurol, Taranto, Italy

[11] Univ Messina, Dept Clin & Expt Med, UOSD Stroke Unit, Messina, Italy

[12] Osped Gen Provinciale M Bufalini, Stroke Unit, AUSL Romagna, Cesena, Italy

[13] Osped Civile Mazzini, Neurol Unit, Teramo, Italy

[14] AOU Consorziale Policlin, UO Neurol & Stroke Unit, Bari, Italy

[15] Padua Univ Hosp, Dept Neurosci, Stroke Unit, Padua, Italy

[16] Padua Univ Hosp, Dept Neurosci, Neurosonol Lab, Padua, Italy

[17] San Giovanni Bosco Hosp, Neurol Unit, Turin, Italy

[18] Azienda Osped Annunziata, Neurol Unit, Cosenza, Italy

[19] Univ Roma Tor Vergata, Dept Syst Med, Rome, Italy

[20] Osped Angelo, USSL3 Serenissima, Neurorol Unit, Venice, Italy

[21] Azienda Osped G Brotzu, Neurosci Dept, Cagliari, Italy

[22] IRCCS Fdn Mondino, UC Malattie Cerebrovascolari & Stroke Unit, Pavia, Italy

[23] Univ Hosp Arcispedale S Anna, Neurol Unit, Ferrara, Italy

[24] Univ Aquila, Dept Appl Clin Sci & Biotechnol, Neurosci Sect, Laquila, Italy

[25] Azienda Osped SS Antonio & Biagio & C Arrigo, Dept Neurol, Alessandria, Italy

[26] Humanitas Clin & Res Ctr IRCCS, Rozzano, MI, Italy

[27] Osped S Maria Misericordia, Stroke Unit, Rovigo, Italy

[28] Azienda Osped Univ Integrata, Neuroradiol Unit, Verona, Italy

[29] Fdn Poliambulanza, Stroke Unit, Brescia, Italy

[30] AUO S Giovanni Dio & Ruggi Aragona, UOC Neuroradiol, Salerno, Italy

[31] Sapienza Univ Rome, Dept Human Neurosci, Emergency Dept, Stroke Unit, Rome, Italy

[32] Osped Univ, Stroke Unit, Parma, Italy

[33] Spedali Civil Brescia, Neurol Unit, Brescia, Italy

[34] Osped Circolo ASST Sette Laghi, Neurol & Stroke Unit, Varese, Italy

[35] Azienda Osped Univ Modena, Dept Neurosci, Neuroradiol Unit, Osped Civile, Modena, Italy

[36] Careggi Univ Hosp, Intervent Neurovasc Unit, Florence, Italy

来源：

JOURNAL OF THROMBOSIS AND THROMBOLYSIS | 2022年 / 54卷 / 02期

关键词：

Collateral score; Thrombectomy; Stroke; Infarct growth; Cerebral edema; Intracerebral hemorrhage; ACUTE ISCHEMIC-STROKE; CT ANGIOGRAPHY; LEPTOMENINGEAL COLLATERALS; ANTERIOR CIRCULATION;

D O I：

10.1007/s11239-022-02647-z

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We aimed to examine the association between Careggi Collateral Score (CCS) and radiological outcomes in a large multicenter cohort of patients receiving thrombectomy for stroke with occlusion of middle cerebral artery (MCA). We conducted a study on prospectively collected data from 1785 patients enrolled in the Italian Registry of Endovascular Treatment in Acute Stroke. According to the extension of the retrograde reperfusion in the cortical anterior cerebral artery-MCA territories, CCS ranges from 0 (absence of retrograde filling) to 4 (visualization of collaterals until the alar segment of the MCA). Radiological outcomes at 24 h were the presence and severity of infarct growth defined by the absolute change in ASPECTS from baseline to 24 h; presence and severity of cerebral bleeding defined as no ICH, HI-1, HI-2, PH-1, or PH-2; presence and severity of cerebral edema (CED) defined as no CED, CED-1, CED-2, or CED-3. Using CCS = 0 as reference, ORs of CCS grades were significantly associated in the direction of better radiological outcome on infarct growth (0.517 for CCS = 1, 0.413 for CCS = 2, 0.358 for CCS = 3, 0.236 for CCS = 4), cerebral bleeding grading (0.485 for CCS = 1, 0.445 for CCS = 2, 0.400 for CCS = 3, 0.379 for CCS = 4), and CED grading (0.734 for CCS = 1, 0.301 for CCS = 2, 0.295 for CCS = 3, 0.255 for CSS = 4) shift in ordinal regression analysis after adjustment for pre-defined variables (age, NIHSS score, ASPECTS, occlusion site, onset-to-groin puncture time, procedure time, and TICI score). Using CCS = 4 as reference, ORs of CCS grades were significantly associated in the direction of worse radiological outcome on infarct growth (1.521 for CCS = 3, 1.754 for CCS = 2, 2.193 for CCS = 1, 4.244 for CCS = 0), cerebral bleeding grading (2.498 for CCS = 0), and CED grading (1.365 for CCS = 2, 2.876 for CCS = 1, 3.916 for CCS = 0) shift. The CCS could improve the prognostic estimate of radiological outcomes in patients receiving thrombectomy for stroke with MCA occlusion.

引用

页码：309 / 317

页数：9

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