Findings in Stillbirths Associated with Placental Disease

被引：21

作者：

Gibbins, Karen J. ^{[1
]}

Pinar, Halit ^{[2
]}

Reddy, Uma M. ^{[3
]}

Saade, George R. ^{[4
]}

Goldenberg, Robert L. ^{[5
]}

Dudley, Donald J. ^{[6
]}

Drews-Botsch, Carolyn ^{[7
]}

Freedman, Alexa Ann ^{[7
]}

Daniels, Lauren M. ^{[7
]}

Parker, Corette B. ^{[8
]}

Thorsten, Vanessa ^{[8
]}

Bukowski, Radek ^{[9
]}

Silver, Robert M. ^{[10
]}

机构：

[1] Oregon Hlth & Sci Univ, Dept Obstet & Gynecol, Div Maternal Fetal Med, L458,3181 Sam Jackson Pk Rd, Portland, OR 97239 USA

[2] Brown Univ, Dept Pathol & Lab Med, Warren Alpert Med Sch, Providence, RI 02912 USA

[3] Yale Sch Med, Dept Obstet & Gynecol, Div Maternal Fetal Med, New Haven, CT USA

[4] Univ Texas Med Branch, Dept Obstet & Gynecol, Div Maternal Fetal Med, Galveston, TX 77555 USA

[5] Columbia Univ, Sch Med, Dept Obstet & Gynecol, New York, NY USA

[6] Univ Virginia, Div Maternal Fetal Med, Dept Obstet & Gynecol, Charlottesville, VA USA

[7] Emory Univ, Dept Epidemiol, Atlanta, GA 30322 USA

[8] RTI Int, Durham, NC USA

[9] Univ Texas Austin, Dept Womens Hlth, Austin, TX 78712 USA

[10] Univ Utah Hlth, Dept Obstet & Gynecol, Div Maternal Fetal Med, Salt Lake City, UT USA

来源：

AMERICAN JOURNAL OF PERINATOLOGY | 2020年 / 37卷 / 07期

关键词：

placental disease; stillbirth; placental insufficiency; placental pathology; PERIVILLOUS FIBRIN DEPOSITION; MATERNAL FLOOR INFARCTION; FETAL-GROWTH RESTRICTION; TOBACCO-SMOKE; UNITED-STATES; RISK-FACTORS; GESTATIONAL-AGE; PREGNANCY; WOMEN; DISPARITIES;

D O I：

10.1055/s-0039-1688472

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Objective Placental disease is a leading cause of stillbirth. Our purpose was to characterize stillbirths associated with placental disease. Study Design The Stillbirth Collaborative Research Network conducted a prospective, case-control study of stillbirths and live births from 2006 to 2008. This analysis includes 512 stillbirths with cause of death assignment and a comparison group of live births. We compared exposures between women with stillbirth due to placental disease and those due to other causes as well as between women with term (>= 37 weeks) stillbirth due to placental disease and term live births. Results A total of 121 (23.6%) out of 512 stillbirths had a probable or possible cause of death due to placental disease by Initial Causes of Fetal Death. Characteristics were similar between stillbirths due to placental disease and other stillbirths. When comparing term live births to stillbirths due to placental disease, women with non-Hispanic black race, Hispanic ethnicity, lack of insurance, or who were born outside of the United States had higher odds of stillbirth due to placental disease. Nulliparity and antenatal bleeding also increased risk of stillbirth due to placental disease. Conclusion Multiple discrete exposures were associated with stillbirth caused by placental disease. The relationship between these factors and utility of surveillance warrants further study.

引用

页码：708 / 715

页数：8