A general method for the Suzuki-Miyaura cross-coupling of sterically hindered aryl chlorides: Synthesis of di- and tri-ortho-substituted biaryls in 2-propanol at room temperature

被引：536

作者：

Navarro, O ^{[1
]}

Kelly, RA ^{[1
]}

Nolan, SP ^{[1
]}

机构：

[1] Univ New Orleans, Dept Chem, New Orleans, LA 70148 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2003年 / 125卷 / 52期

关键词：

D O I：

10.1021/ja038631r

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The catalytic formation of di- and trisubstituted ortho biaryl junctions has been achieved using a palladacylce pre-catalyst bearing a N-heterocyclic carbene ligand. This transformation is performed at room temperature in technical grade 2-propanol. Copyright © 2003 American Chemical Society.

引用

页码：16194 / 16195

页数：2

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