MET exon 14 Mutations Encode a Hyperactive Kinase and Therapeutic Target in Lung Adenocarcinoma

被引:0
作者
Peled, Nir [1 ]
Lu, Xinyuan [2 ]
Greer, John [2 ]
Wu, Wei [2 ]
Choi, Peter [3 ]
Berger, Alice [3 ]
Hann, Byron [2 ]
Meyerson, Matthew [4 ,5 ]
Collisson, Eric [2 ]
机构
[1] Rabin Med Ctr, Tel Aviv, Israel
[2] UCSF, San Francisco, CA USA
[3] Dana Farber Canc Inst, Med Oncol, Boston, MA 02115 USA
[4] Broad Inst Harvard & Mit, Dana Farber Canc Inst, Boston, MA USA
[5] Massachusetts Gen Hosp, Boston, MA 02114 USA
关键词
MET; Resistance; Targeted therapy; Mouse model;
D O I
10.1016/j.jtho.2016.11.1323
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
P2.03b042
引用
收藏
页码:S961 / S961
页数:1
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