Quantitative Particle Uptake by Cells as Analyzed by Different Methods

被引：53

作者：

Ashraf, Sumaira ^{[1
,2
]}

Hassan Said, Alaa ^{[1
,3
]}

Hartmann, Raimo ^{[1
]}

Assmann, Marcus-Alexander ^{[1
,4
]}

Feliu, Neus ^{[5
]}

Lenz, Peter ^{[1
]}

Parak, Wolfgang J. ^{[5
,6
]}

机构：

[1] Philipps Univ Marburg, Fachbereich Phys, D-35037 Marburg, Germany

[2] Govt Coll Univ, Inst Ind Biotechnol, Lahore 54000, Punjab, Pakistan

[3] South Valley Univ, Fac Sci, Dept Phys, Elect & Nano Devices Lab END, Qena 83523, Egypt

[4] Ernst Mach Inst, Fraunhofer Inst High Speed Dynam, D-79104 Freiburg, Germany

[5] Univ Hamburg, CHyN, Fachbereich Phys & Chem, D-20146 Hamburg, Germany

[6] Shanghai Jiao Tong Univ, Key Lab Thin Film & Microfabricat Technol, Sch Elect Informat & Elect Engn, Minist Educ,Dept Instrument Sci & Engn,Inst Nano, Shanghai, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2020年 / 59卷 / 14期

关键词：

bioanalytics; cells; nanoparticles; particle uptake; POLYMER-COATED NANOPARTICLES; IRON-OXIDE NANOPARTICLES; CELLULAR UPTAKE; IN-VITRO; GOLD NANOPARTICLES; QUANTUM DOTS; UPTAKE MECHANISMS; ENDOCYTIC UPTAKE; MAMMALIAN-CELLS; PROTEIN CORONA;

D O I：

10.1002/anie.201906303

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

There is a large number of two-dimensional static in vitro studies about the uptake of colloidal nano- and microparticles, which has been published in the last decade. In this Minireview, different methods used for such studies are summarized and critically discussed. Supplementary experimental data allow for a direct comparison of the different techniques. Emphasis is given on how quantitative parameters can be extracted from studies in which different experimental techniques have been used, with the goal of allowing better comparison.

引用

页码：5438 / 5453

页数：16

共 156 条

[1] New directions in quantum dot-based cytometry detection of cancer serum markers and tumor cells [J].