The arduous road to achieving an immunosuppression-free state in kidney transplant recipients

被引：4

作者：

Ansari, M. Javeed

Sayegh, Mohamed H.

机构：

[1] Brigham & Womens Hosp, Transplantat Res Ctr, Div Renal, Boston, MA 02115 USA

[2] Harvard Univ, Sch Med, Boston, MA USA

[3] Harvard Univ, Sch Med, Warren E Grp, Boston, MA USA

[4] Harvard Univ, Sch Med, John P Merrill Chair Transplantat Med, Boston, MA USA

来源：

NATURE CLINICAL PRACTICE NEPHROLOGY | 2007年 / 3卷 / 09期

关键词：

D O I：

10.1038/ncpneph0568

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Since the first successful transplantations were performed around 50 years ago, the lack of improvement in long-term graft survival and the risks associated with immunosuppressive therapy have made the ability to induce tolerance a burning desire among transplantation immunobiologists. These authors outline the considerable challenges that stand in the way of this goal, and proffer their opinion on which strategies are most likely to succeed.

引用

页码：464 / 465

页数：2

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