Reversed end-diastolic flow in first-trimester umbilical artery: An ominous new sign for fetal outcome

被引：11

作者：

Borrell, A ^{[1
]}

Martinez, JM ^{[1
]}

Farre, MT ^{[1
]}

Azulay, M ^{[1
]}

Cararach, V ^{[1
]}

Fortuny, A ^{[1
]}

机构：

[1] Univ Barcelona, Sch Med, Hosp Clin,IDIBAPS, Inst Gynecol Obstet & Neonatol,Prenatal Diag Unit, Barcelona 08036, Spain

来源：

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | 2001年 / 185卷 / 01期

关键词：

chromosomal anomaly; congenital heart disease; Doppler studies; nuchal translucency; reversed end-diastolic flow; umbilical artery;

D O I：

10.1067/mob.2001.114872

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

OBJECTIVE: The purpose of this study was to assess the fetal outcome of first-trimester pregnancies with reversed end-diastolic flow in the umbilical artery. STUDY DESIGN: Doppler studies in the umbilical artery were carried out in 2970 consecutive pregnancies scanned at 10 to 14 weeks. RESULTS: We observed 11 (0.4%) cases of reversed end-diastolic flow. Of these, an autosomal trisomy was shown in 7 and a congenital heart defect in 2 additional fetuses. Fetal demise was observed in 5 pregnancies, neonatal death was observed in 1, and termination of pregnancy was carried out in 4. Only 1 fetus survived. CONCLUSIONS: Reversed end-diastolic flow in first-trimester umbilical artery signals an ominous prognosis even with normal karyotype.

引用

页码：204 / 207

页数：4

共 23 条

[1] DOPPLER ULTRASONOGRAPHY IN HIGH-RISK PREGNANCIES - SYSTEMATIC REVIEW WITH METAANALYSIS [J].