Palladium-Catalyzed C3-Benzylation of Indoles

被引：128
作者：
Zhu, Ye [1 ]
Rawal, Viresh H. [1 ]
机构：
[1] Univ Chicago, Dept Chem, Chicago, IL 60637 USA
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2012年 / 134卷 / 01期
基金：
美国国家卫生研究院;
关键词：
2,3-DISUBSTITUTED INDOLES; FUNCTIONALIZATION; DERIVATIVES; ALKYLATION; ALLYLATION; HYDROAMINATION; SUBSTITUTION; BENZYLATION; VINYLARENES; OXINDOLES;
D O I：
10.1021/ja2095393
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A general method for regioselective C3-benzylation of indoles has been developed. Various 3-substituted indoles and benzyl methyl carbonates with different electronic properties react under mild conditions to afford a diverse range of 3-benzylindolenine products in good yields.
引用
收藏
页码：111 / 114
页数：4
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