Impact of Obstructive Sleep Apnea and Current Treatments on the Development and Progression of Type 2 Diabetes

被引：8

作者：

Faria, Andre ^{[1
]}

Laher, Ismail ^{[2
]}

Fasipe, Babatunde ^{[3
]}

Ayas, Najib T. ^{[4
,5
]}

机构：

[1] Univ Fed Minas Gerais, Fac Med, Belo Horizonte, MG, Brazil

[2] Univ British Columbia, Fac Med, Dept Anesthesiol Pharmacol & Therapeut, Vancouver, BC, Canada

[3] Bowen Univ, Fac Basic Clin Sci, Dept Pharmacol & Therapeut, Iwo, Nigeria

[4] Univ British Columbia, Div Crit Care, Vancouver, BC, Canada

[5] Univ British Columbia, Div Resp Med, Vancouver, BC, Canada

来源：

CURRENT DIABETES REVIEWS | 2022年 / 18卷 / 09期

关键词：

Obstructive sleep apnea; type; 2; diabetes; insulin resistance; treatments; CPAP; oral appliances; weight loss; POSITIVE AIRWAY PRESSURE; INTERMITTENT HYPOXIA; INSULIN-RESISTANCE; CONTROLLED-TRIAL; ADIPOSE-TISSUE; WEIGHT-LOSS; RISK-FACTOR; PREVALENCE; GLUCOSE; INFLAMMATION;

D O I：

10.2174/1573399818666220216095848

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Type 2 diabetes mellitus remains a growing health concern, affecting more than 420 million people globally. Preventing and treating diabetes require a better understanding of the associated risk factors. Sleep-disordered breathing, especially obstructive sleep apnea (OSA), is likely a contributor to the pathogenesis and aggravation of poor glycemic control. We review key epidemiological data that address the link between OSA and type 2 diabetes and present the current proposed pathophysiological mechanisms underlying this association. Several biological pathways are linking OSA and an increased propensity to diabetes. We review the impact of current treatment strategies for OSA based on the association between diabetes and sleep apnea.

引用

页码：25 / 32

页数：8

共 56 条

[11] Continuous positive airway pressure and diabetes risk in sleep apnea patients: A systemic review and meta-analysis [J].

Chen, Liang ;

Kuang, Jian ;

Pei, Jian-Hao ;

Chen, Hong-Mei ;

Chen, Zhong ;

Li, Zhong-Wen ;

Yang, Hua-Zhang ;

Fu, Xiao-Ying ;

Wang, Long ;

Chen, Zhi-Jiang ;

Lai, Shui-Qing ;

Zhang, Shu-Ting .

EUROPEAN JOURNAL OF INTERNAL MEDICINE, 2017, 39 :39-50

[12] CPAP, Weight Loss, or Both for Obstructive Sleep Apnea [J].

Chirinos, Julio A. ;

Gurubhagavatula, Indira ;

Teff, Karen ;

Rader, Daniel J. ;

Wadden, Thomas A. ;

Townsend, Raymond ;

Foster, Gary D. ;

Maislin, Greg ;

Saif, Hassam ;

Broderick, Preston ;

Chittams, Jesse ;

Hanlon, Alexandra L. ;

Pack, Allan I. .

NEW ENGLAND JOURNAL OF MEDICINE, 2014, 370 (24) :2265-2275

[13] EPINEPHRINE-INDUCED INSULIN RESISTANCE IN MAN [J].

DEIBERT, DC ;

DEFRONZO, RA .

JOURNAL OF CLINICAL INVESTIGATION, 1980, 65 (03) :717-721

[14] Chronic Intermittent Hypoxia Induces Atherosclerosis via Activation of Adipose Angiopoietin-like 4 [J].

Drager, Luciano F. ;

Yao, Qiaoling ;

Hernandez, Karen L. ;

Shin, Mi-Kyung ;

Bevans-Fonti, Shannon ;

Gay, Jason ;

Sussan, Thomas E. ;

Jun, Jonathan C. ;

Myers, Allen C. ;

Olivecrona, Gunilla ;

Schwartz, Alan R. ;

Halberg, Nils ;

Scherer, Philipp E. ;

Semenza, Gregg L. ;

Powell, David R. ;

Polotsky, Vsevolod Y. .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2013, 188 (02) :240-248

[15] Obstructive sleep apnea-hypopnea and related clinical features in a population-based sample of subjects aged 30 to 70 yr [J].

Durán, J ;

Esnaola, S ;

Rubio, R ;

Iztueta, A .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2001, 163 (03) :685-689

[16] Effects of continuous positive airway pressure therapy on glycaemic control, insulin sensitivity and body mass index in patients with obstructive sleep apnoea and type 2 diabetes: a systematic review and meta-analysis [J].

Feng, Ye ;

Zhang, Zhe ;

Dong, Zhou-zhou .

NPJ PRIMARY CARE RESPIRATORY MEDICINE, 2015, 25

[17] A Mouse Model of Metabolic Syndrome: Insulin Resistance, Fatty Liver and Non-Alcoholic Fatty Pancreas Disease (NAFPD) in C57BL/6 Mice Fed a High Fat Diet [J].

Fraulob, Julio C. ;

Ogg-Diamantino, Rebeca ;

Fernandes-Santos, Caroline ;

Aguila, Marcia Barbosa ;

Mandarim-de-Lacerda, Carlos A. .

JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION, 2010, 46 (03) :212-223

[18] The Role of Oxidative Stress and Hypoxia in Pancreatic Beta-Cell Dysfunction in Diabetes Mellitus [J].

Gerber, Philipp A. ;

Rutter, Guy A. .

ANTIOXIDANTS & REDOX SIGNALING, 2017, 26 (10) :501-+

[19] Prevalence of sleep-disordered breathing in the general population: the HypnoLaus study [J].

Heinzer, R. ;

Vat, S. ;

Marques-Vidal, P. ;

Marti-Soler, H. ;

Andries, D. ;

Tobback, N. ;

Mooser, V. ;

Preisig, M. ;

Malhotra, A. ;

Waeber, G. ;

Vollenweider, P. ;

Tafti, M. ;

Haba-Rubio, J. .

LANCET RESPIRATORY MEDICINE, 2015, 3 (04) :310-318

[20] Cardiometabolic changes after continuous positive airway pressure for obstructive sleep apnoea: a randomised sham-controlled study [J].

Hoyos, Camilla M. ;

Killick, Roo ;

Yee, Brendon J. ;

Phillips, Craig L. ;

Grunstein, Ronald R. ;

Liu, Peter Y. .

THORAX, 2012, 67 (12) :1081-1089

← 1 2 3 4 5 6 →