Cardiovascular complications in acromegaly

被引：1
作者：
Sagova, Ivana [1 ,2 ,3 ]
Kantarova, Daniela [2 ,3 ]
Mokan, Marian [2 ,3 ]
Dragula, Milan [4 ]
Vanuga, Peter [1 ]
机构：
[1] Narodny Endokrinol & Diabetol Ustav No, Endokrinol Oddelenie, Lubochna, Slovakia
[2] Jesseniova Lekarska Fak Martine, Interna Klin 1, Martin, Slovakia
[3] Univ Nemocnica Martin, Martin, Slovakia
[4] Univ Nemocnica Martin, Kardiol Oddelenie, Martin, Slovakia
来源：
COR ET VASA | 2022年 / 64卷 / 01期
关键词：
Acromegaly; Cardiovascular complications; Growth hormone; Insulin-like growth factor 1; HORMONE-RECEPTOR ANTAGONIST; GROWTH-FACTOR-I; LONG-TERM; ENDOTHELIAL DYSFUNCTION; SOMATOSTATIN ANALOGS; CARDIAC STRUCTURE; HIGH PREVALENCE; HEART-DISEASE; RISK-FACTORS; PEGVISOMANT;
D O I：
10.33678/cor.2021.105
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Acromegaly is a rare, chronic, progressive disease which is usually caused by a pituitary adenoma. Long-term presence of elevated growth hormone (GH) and insulin-like growth factor 1 (IGF-1) levels accompanying this disease is associated with rheumatologic, cardiovascular, pulmonary and metabolic complications. Cardiovascular disorders are the leading cause of morbidity and mortality in patients with acromegaly. Cardiovascular complications of acromegaly include an arterial hypertension, cardiomyopathy, arrhytmias, valvulopathy as well as endothelial dysfunction. The diagnosis of acromegaly has been delayed for several years due to slow progression of symptoms. Early diagnosis and treatment of the disease is necessary to prevent chronic cardiovascular damage.
引用
收藏
页码：46 / 52
页数：7
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