SPARSEMODr: Rapidly simulate spatially explicit and stochastic models of COVID-19 and other infectious diseases

被引:2
|
作者
Mihaljevic, Joseph R. [1 ]
Borkovec, Seth [1 ]
Ratnavale, Saikanth [1 ]
Hocking, Toby D. [1 ]
Banister, Kelsey E. [1 ]
Eppinger, Joseph E. [1 ]
Hepp, Crystal [1 ,2 ,3 ]
Doerry, Eck [1 ]
机构
[1] No Arizona Univ, Sch Informat Comp & Cyber Syst, Flagstaff, AZ 86011 USA
[2] No Arizona Univ, Pathogen & Microbiome Inst, Flagstaff, AZ 86011 USA
[3] Translat Genom Res Inst, Pathogen & Microbiome Div, Flagstaff, AZ 86005 USA
来源
BIOLOGY METHODS & PROTOCOLS | 2022年 / 7卷 / 01期
基金
美国国家科学基金会;
关键词
epidemiological model; spatial disease models; R; C plus plus; disease ecology; host-pathogen interactions; TRANSMISSION; VACCINATION; EPIDEMIC; DYNAMICS;
D O I
10.1093/biomethods/bpac022
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Building realistically complex models of infectious disease transmission that are relevant for informing public health is conceptually challenging and requires knowledge of coding architecture that can implement key modeling conventions. For example, many of the models built to understand COVID-19 dynamics have included stochasticity, transmission dynamics that change throughout the epidemic due to changes in host behavior or public health interventions, and spatial structures that account for important spatio-temporal heterogeneities. Here we introduce an R package, SPARSEMODr, that allows users to simulate disease models that are stochastic and spatially explicit, including a model for COVID-19 that was useful in the early phases of the epidemic. SPARSEMOD stands for SPAtial Resolution-SEnsitive Models of Outbreak Dynamics, and our goal is to demonstrate particular conventions for rapidly simulating the dynamics of more complex, spatial models of infectious disease. In this report, we outline the features and workflows of our software package that allow for user-customized simulations. We believe the example models provided in our package will be useful in educational settings, as the coding conventions are adaptable, and will help new modelers to better understand important assumptions that were built into sophisticated COVID-19 models.
引用
收藏
页数:9
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