Genetics and male infertility

被引：22

作者：

Hargreave, TB ^{[1
]}

机构：

[1] Western Gen Hosp, Dept Urol, Fertil Problems Clin, Edinburgh EH4 2XU, Midlothian, Scotland

来源：

CURRENT OPINION IN OBSTETRICS & GYNECOLOGY | 2000年 / 12卷 / 03期

关键词：

D O I：

10.1097/00001703-200006000-00008

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

This article reviews chromosomal and genetic disorders in the context of male fertility. Particular emphasis is on those disorders, which are encountered, in clinical practice including Klinefelter's syndrome, Kallman's syndrome, Androgen insensitivity, Y microdeletions, Y fertility gene deletions, and cystic fibrosis gene mutations. These disorders are discussed in relation to the aetiology of male fertility and also risks to children who are born of fathers with these disorders. A list of fathers' categories is proposed for outcome studies for children born after IVF-ICSI, Finally a question is proposed to catalyse debate about germ line therapy. (C) 2000 Lippincott Williams & Wilkins.

引用

页码：207 / 219

页数：13

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