Expeditious Synthesis of [Au(NHC)(L)]+ (NHC = N-Heterocyclic Carbene; L = Phosphine or NHC) Complexes

被引：85

作者：

Gaillard, Sylvain ^{[1
]}

Nun, Pierrick ^{[1
]}

Slawin, Alexandra M. Z. ^{[1
]}

Nolan, Steven P. ^{[1
]}

机构：

[1] Univ St Andrews, Sch Chem, St Andrews KY16 9ST, Fife, Scotland

来源：

ORGANOMETALLICS | 2010年 / 29卷 / 21期

基金：

英国工程与自然科学研究理事会;

关键词：

GOLD(I) COMPLEXES; ANTICANCER; CYTOTOXICITY; LIGANDS; BEARING;

D O I：

10.1021/om100456b

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The use of the versatile N-heterocyclic carbene (NHC) gold(I) hydroxide [Au(OH)(IPr)] (IPr = N,N '-bis(2,6-diisopropylpheny)imidazol-2-ylidene) as precursor permits the expedient synthesis of a series of cationic heteroleptic [Au(NHC)(NHC')](+) and [Au(NHC)(PR3)](+) complexes by proton. lysis with the appropriate acid salts. Complete characterization by H-1 and C-13 NMR spectroscopy and by single-crystal X-ray diffraction was performed in order to discern electronic and structural differences between cationic heteroleptic [Au(NHC)(NHC')](+) and [Au(NHC)(PR3)](+) congeners.

引用

页码：5402 / 5408

页数：7

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