Bone scintigraphy imaging of cardiac amyloidosis

被引：7

作者：

Kuria, Issa Menge ^{[1
]}

Gitau, Samuel Nguku ^{[1
]}

Makhdomi, Khalid Bashir ^{[1
]}

机构：

[1] Aga Khan Univ Hosp, Dept Imaging & Diagnost Radiol, Nairobi, Kenya

来源：

WORLD JOURNAL OF NUCLEAR MEDICINE | 2019年 / 18卷 / 03期

关键词：

AL; bone scintigraphy; cardiac amyloidosis; transthyretin ATTR;

D O I：

10.4103/wjnm.WJNM_9_19

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Transthyretin-related cardiac amyloidosis (ATTR) amyloidosis is an aggressive, rapidly progressive, and fatal disease, for which several promising therapies are in development. This condition is frequently underdiagnosed because of the limited specificity of echocardiography and the traditional requirement for histological diagnosis. It is well known that 99mtechnetium-labeled bone scan radiotracers can localize in the myocardial amyloid deposits, but the use of this imaging modality to differentiate between the two subtypes has only lately been revisited. We report a case of a 76-year-old man with a clinical diagnosis of amyloidosis who underwent a bone scan that had features of ATTR amyloidosis. To the best of our knowledge, this is the first case report in Sub-Saharan Africa.

引用

页码：314 / 316

页数：3

共 20 条

[1] Myocardial Tc-99m MDP uptake on a bone scan in senile systemic amyloidosis with cardiac involvement [J].

Ak, I ;

Vardareli, E ;

Erdinc, O ;

Kasapoglu, E ;

Ata, N .

CLINICAL NUCLEAR MEDICINE, 2000, 25 (10) :826-827

[2]

ALI A, 1981, Clinical Nuclear Medicine, V6, P105, DOI 10.1097/00003072-198103000-00003

[3]

[Anonymous], 2018, FDA approves new treatment for moderately to severely active ulcerative colitis"

[4] Fine-needle aspiration of abdominal fat pad for amyloid detection: A clinically useful test? [J].

Ansari-Lari, MA ;

Ali, SZ .

DIAGNOSTIC CYTOPATHOLOGY, 2004, 30 (03) :178-181

[5] 99mTc-Pyrophosphate Scintigraphy for Differentiating Light-Chain Cardiac Amyloidosis From the Transthyretin-Related Familial and Senile Cardiac Amyloidoses [J].

Bokhari, Sabahat ;

Castano, Adam ;

Pozniakoff, Ted ;

Deslisle, Susan ;

Latif, Farhana ;

Maurer, Mathew S. .

CIRCULATION-CARDIOVASCULAR IMAGING, 2013, 6 (02) :195-201

[6] The transthyretin amyloidoses: advances in therapy [J].

Dubrey, Simon ;

Ackermann, Elizabeth ;

Gillmore, Julian .

POSTGRADUATE MEDICAL JOURNAL, 2015, 91 (1078) :439-448

[7] Diagnosis and management of the cardiac amyloidoses [J].

Falk, RH .

CIRCULATION, 2005, 112 (13) :2047-2060

[8] Nonbiopsy Diagnosis of Cardiac Transthyretin Amyloidosis [J].

Gillmore, Julian D. ;

Maurer, Mathew S. ;

Falk, Rodney H. ;

Merlini, Giampaolo ;

Damy, Thibaud ;

Dispenzieri, Angela ;

Wechalekar, Ashutosh D. ;

Berk, John L. ;

Quarta, Candida C. ;

Grogan, Martha ;

Lachmann, Helen J. ;

Bokhari, Sabahat ;

Castano, Adam ;

Dorbala, Sharmila ;

Johnson, Geoff B. ;

Glaudemans, Andor W. J. M. ;

Rezk, Tamer ;

Fontana, Marianna ;

Palladini, Giovanni ;

Milani, Paolo ;

Guidalotti, Pierluigi L. ;

Flatman, Katarina ;

Lane, Thirusha ;

Vonberg, Frederick W. ;

Whelan, Carol J. ;

Moon, James C. ;

Ruberg, Frederick L. ;

Miller, Edward J. ;

Hutt, David F. ;

Hazenberg, Bouke P. ;

Rapezzi, Claudio ;

Hawkins, Philip N. .

CIRCULATION, 2016, 133 (24) :2404-+

[9] Prognostic utility of the Perugini grading of 99mTc-DPD scintigraphy in transthyretin (ATTR) amyloidosis and its relationship with skeletal muscle and soft tissue amyloid [J].

Hutt, David F. ;

Fontana, Marianna ;

Burniston, Maria ;

Quigley, Ann-Marie ;

Petrie, Aviva ;

Ross, James C. ;

Page, Joanne ;

Martinez-Naharro, Ana ;

Wechalekar, Ashutosh D. ;

Lachmann, Helen J. ;

Quarta, Candida C. ;

Rezk, Tamer ;

Mahmood, Shameem ;

Sachchithanantham, Sajitha ;

Youngstein, Taryn ;

Whelan, Carol J. ;

Lane, Thirusha ;

Gilbertson, Janet A. ;

Rowczenio, Dorota ;

Hawkins, Philip N. ;

Gillmore, Julian D. .

EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING, 2017, 18 (12) :1344-1350

[10] Utility and limitations of 3,3-diphosphono-1,2-propanodicarboxylic acid scintigraphy in systemic amyloidosis [J].

Hutt, David F. ;

Quigley, Anne-Marie ;

Page, Joanne ;

Hall, Margaret L. ;

Burniston, Maria ;

Gopaul, Dorothea ;

Lane, Thirusha ;

Whelan, Carol J. ;

Lachmann, Helen J. ;

Gillmore, Julian D. ;

Hawkins, Philip N. ;

Wechalekar, Ashutosh D. .

EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING, 2014, 15 (11) :1289-1298

← 1 2 →