Secondary metabolites from Calotropis procera (Aiton)

被引：43
|
作者：
Shaker, Kamel H. [1 ]
Morsy, Nagy [2 ]
Zinecker, Heidi [3 ]
Imhoff, Johannes F. [3 ]
Schneider, Bernd [1 ]
机构：
[1] Max Planck Inst Chem Ecol, D-07745 Jena, Germany
[2] Natl Res Ctr, Cairo, Egypt
[3] IFM GEOMAR, Kieler Wirkstoff Zentrum, D-24106 Kiel, Germany
来源：
PHYTOCHEMISTRY LETTERS | 2010年 / 3卷 / 04期
关键词：
Calotropis procera; Asclepiadaceae; Cardenolides; Flavones; Glycosides; PENTACYCLIC TRITERPENE; CARDENOLIDES;
D O I：
10.1016/j.phytol.2010.07.009
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Three new metabolites, 5-hydroxy-3,7-dimethoxyflavone-4'-O-beta-glucopyranoside (1), 2 beta,19-epoxy-3 beta,14 beta-dihydroxy-19-methoxy-5 alpha-card-20(22)-enolide (4) and beta-anhydroepidigitoxigenin-3 beta-O-glucopyranoside (5), along with two known compounds, uzarigenine (2) and beta-anhydroepidigitoxigenin (3), were isolated from Calotropis procera (Asclepiadaceae). The structure elucidation was accomplished mainly by nuclear magnetic resonance (NMR) spectroscopic and mass spectrometric methods. To examine putative antimicrobial or cytotoxic activities, various bioassays were performed. Uzarigenine (2) demonstrated moderate cytotoxicity. (C) 2010 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码：212 / 216
页数：5
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