Effect of Ablation for Atrial Fibrillation on Heart Failure Readmission Rates

被引:15
作者
Joy, Parijat Saurav [1 ]
Gopinathannair, Rakesh [2 ]
Olshansky, Brian [1 ]
机构
[1] Univ Iowa Hosp & Clin, Dept Med, Iowa City, IA 52242 USA
[2] Univ Louisville, Dept Med, Louisville, KY 40292 USA
关键词
PULMONARY-VEIN ISOLATION; CATHETER ABLATION; EPIDEMIOLOGY; DYSFUNCTION; PREVALENCE; TRIAL;
D O I
10.1016/j.amjcard.2017.07.057
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Atrial fibrillation (AF) and heart failure (HF) cause numerous hospital admissions. We investigated if AF increases readmissions in patients with HF and whether AF ablation alters readmissions for HF exacerbations. The 2013 Nationwide Readmissions Database was analyzed for all-cause 90-day readmissions, after discharge for HF exacerbation. Kaplan-Meier analysis was used to compare hazard rates for readmissions due to HF exacerbation, after recent ablation versus no ablation. There were 885,270 admissions for HF exacerbation of which 364,447 had coexisting AF. All-cause 90-day readmission rates were higher in patients with HF with coexisting AF versus those without AF (41.4% vs 37.6%, p <0.0001). Associated factors increasing all-cause 90-day readmissions after ablation in patients without HF were female (odds ratio [OR] 1.44, p <0.001), complication of ablation (OR 1.44, p = 0.022), coronary artery disease (OR 1.56, p <0.001), chronic lung disease (OR 1.74, p <0.001), and malnutrition (OR 10.33, p <0.001). These factors were not significant for patients with HF. HF was not a significant risk factor for complications of ablation (adjusted OR 0.82, 95% confidence interval 0.57 to 1.18). Patients who underwent ablation versus patients who were discharged after HF exacerbation without ablation had a lower rate and length of stay for the 90-day readmission episode, due to HF exacerbation (27.5% vs 41.4%, p <0.0001, and 5.58 days vs 6.60 days, p = 0.031, respectively). In conclusion, AF increased 90-day readmissions in patients with HF, and ablation for AF in patients with HF was associated with reduced frequency, length of stay, and readmissions without an increase in complication rates. (C) 2017 Published by Elsevier Inc.
引用
收藏
页码:1572 / 1577
页数:6
相关论文
共 18 条
[1]   Quantifying the heart failure epidemic: prevalence, incidence rate, lifetime risk and prognosis of heart failure - The Rotterdam Study [J].
Bleumink, GS ;
Knetsch, AM ;
Sturkenboom, MCJM ;
Straus, SMJM ;
Hofman, A ;
Deckers, JW ;
Witteman, JCM ;
Stricker, BHC .
EUROPEAN HEART JOURNAL, 2004, 25 (18) :1614-1619
[2]   Shattuck lecture - Cardiovascular medicine at the turn of the millennium: Triumphs, concerns, and opportunities [J].
Braunwald, E .
NEW ENGLAND JOURNAL OF MEDICINE, 1997, 337 (19) :1360-1369
[3]   Pulmonary vein isolation for the treatment of atrial fibrillation in patients with impaired systolic function [J].
Chen, MS ;
Marrouche, NF ;
Khaykin, Y ;
Gillinov, AM ;
Wazni, O ;
Martin, DO ;
Rossillo, A ;
Verma, A ;
Cummings, J ;
Erciyes, D ;
Saad, E ;
Bhargava, M ;
Bash, D ;
Schweikert, R ;
Burkhardt, D ;
Williams-Andrews, M ;
Perez-Lugones, A ;
Abdul-Karim, A ;
Saliba, W ;
Natale, A .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2004, 43 (06) :1004-1009
[4]   Worldwide Epidemiology of Atrial Fibrillation A Global Burden of Disease 2010 Study [J].
Chugh, Sumeet S. ;
Havmoeller, Rasmus ;
Narayanan, Kumar ;
Singh, David ;
Rienstra, Michiel ;
Benjamin, Emelia J. ;
Gillum, Richard F. ;
Kim, Young-Hoon ;
McAnulty, John H. ;
Zheng, Zhi-Jie ;
Forouzanfar, Mohammad H. ;
Naghavi, Mohsen ;
Mensah, George A. ;
Ezzati, Majid ;
Murray, Christopher J. L. .
CIRCULATION, 2014, 129 (08) :837-847
[5]   Estimates of Current and Future Incidence and Prevalence of Atrial Fibrillation in the US Adult Population [J].
Colilla, Susan ;
Crow, Ann ;
Petkun, William ;
Singer, Daniel E. ;
Simon, Teresa ;
Liu, Xianchen .
AMERICAN JOURNAL OF CARDIOLOGY, 2013, 112 (08) :1142-1147
[6]   Ablation Versus Amiodarone for Treatment of Persistent Atrial Fibrillation in Patients With Congestive Heart Failure and an Implanted Device: Results From the AATAC Multicenter Randomized Trial [J].
Di Biase, Luigi ;
Mohanty, Prasant ;
Mohanty, Sanghamitra ;
Santangeli, Pasquale ;
Trivedi, Chintan ;
Lakkireddy, Dhanunjaya ;
Reddy, Madhu ;
Jais, Pierre ;
Themistoclakis, Sakis ;
Dello Russo, Antonio ;
Casella, Michela ;
Pelargonio, Gemma ;
Narducci, Maria Lucia ;
Schweikert, Robert ;
Neuzil, Petr ;
Sanchez, Javier ;
Horton, Rodney ;
Beheiry, Salwa ;
Hongo, Richard ;
Hao, Steven ;
Rossillo, Antonio ;
Forleo, Giovanni ;
Tondo, Claudio ;
Burkhardt, J. David ;
Haissaguerre, Michel ;
Natale, Andrea .
CIRCULATION, 2016, 133 (17) :1637-1644
[7]   The impairment of health-related quality of life in patients with intermittent atrial fibrillation: Implications for the assessment of investigational therapy [J].
Dorian, P ;
Jung, W ;
Newman, D ;
Paquette, M ;
Wood, K ;
Ayers, GM ;
Camm, J ;
Akhtar, M ;
Luderitz, B .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2000, 36 (04) :1303-1309
[8]   Reversal of left ventricular dysfunction following ablation of atrial fibrillation [J].
Gentlesk, Philip J. ;
Sauer, William H. ;
Gerstenfeld, Edward P. ;
Lin, David ;
Dixit, Sanjay ;
Zado, Erica ;
Callans, Pa-C David ;
Marchlinski, Francis E. .
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, 2007, 18 (01) :9-14
[9]   THE EPIDEMIOLOGY OF HEART-FAILURE - THE FRAMINGHAM-STUDY [J].
HO, KKL ;
PINSKY, JL ;
KANNEL, WB ;
LEVY, D .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1993, 22 (04) :A6-A13
[10]  
Hospital cost and utilization project (HCUP), 2012, HCUP NAT INP SAMPL N