Novel Green Procedure for the Synthesis of 2-Arylbenzothiazoles Under Microwave Irradiation in Peg 200 Or Peg 400

被引：34

作者：

Deligeorgiev, Todor G. ^{[1
]}

Kaloyanova, Stefka ^{[1
]}

Vasilev, Aleksey ^{[1
]}

Vaquero, Juan J. ^{[2
]}

机构：

[1] Univ Sofia, Fac Chem, Sofia 1164, Bulgaria

[2] Univ Alcala, Fac Farm, Madrid, Spain

来源：

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 2010年 / 185卷 / 11期

关键词：

2-Aminothiophenols; arylbenzothiazoles; 2; 2'-diaminodiphenyldisulfides; green chemistry; microwave; SOLVENT-FREE SYNTHESIS; EFFICIENT SYNTHESIS; ANTITUMOR BENZOTHIAZOLES; CONDENSATION; DERIVATIVES; FACILE;

D O I：

10.1080/10426501003598648

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

An improved green procedure for the synthesis of 2-aryl- and 2-hetarylbenzothiazoles by condensation of equivalent amounts of 2,2'-diaminodiphenyldisulfides or 2-aminothiophenols and various aromatic aldehydes in PEG 200/400 under microwave irradiation has been developed. This method allows the synthesis of 2-arylbenzothiazoles in high yields and with high purity regardless of the state of the starting compounds (liquid or solid) or the nature of the substituents in the aromatic ring.

引用

收藏

页码：2292 / 2302

页数：11

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