Cell division tracking and expansion of hematopoietic long-term repopulating cells

被引：17
|
作者：
Oostendorp, RAJ
Audet, J
Miller, C
Eaves, CJ
机构：
[1] British Columbia Canc Agcy, Terry Fox Lab, Vancouver, BC V5Z 1L3, Canada
[2] GSF Munich, Res Ctr Environm & Hlth, Munich, Germany
来源：
LEUKEMIA | 1999年 / 13卷 / 04期
关键词：
stem cells; self renewal; in vitro expansion;
D O I：
10.1038/sj.leu.2401373
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The combined use of rigorous assays for quantitating transplantable stem cell numbers and precise cell labeling and tracking procedures have provided definitive evidence that stem cell self-renewal divisions can occur in vitro in the absence of stromal feeder layers. These findings set the stage for defining conditions that may alter the ability of these cells to maintain their primitive status when mitogenically activated.
引用
收藏
页码：499 / 501
页数：3
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