Changes in organ donor epidemiology and new strategies for kidney preservation

被引:1
作者
Barrou, Benoit [1 ]
机构
[1] Univ Paris 06, Fac Med, GH Pitie Salpetriere,Grp Rech Flirt, Inserm Poitiers U 927,Plateforme IBISA INRA Surg, F-75252 Paris 05, France
来源
BULLETIN DE L ACADEMIE NATIONALE DE MEDECINE | 2011年 / 195卷 / 4-5期
关键词
KIDNEY TRANSPLANTATION; ISCHEMIA; REPERFUSION; PULSATILE PERFUSION PRESERVATION; HEART-BEATING DONORS; MACHINE PERFUSION; RENAL-TRANSPLANTATION; ALLOGRAFTS; OUTCOMES; INJURY;
D O I
10.1016/S0001-4079(19)32040-0
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Changes in the epidemiology of brain death are leading the transplant community to use more marginal grafts from so-called extended criteria donors. Current preservation techniques, while simple, are no longer adequate for these organs, which harbor chronic lesions making them very sensitive to ischemia-reperfusion injury. New preservation solutions are needed, along with machine perfusion techniques (dynamic preservation) and normothermic preservation phases.
引用
收藏
页码:883 / 896
页数:14
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