Methods to measure T-cell responses

被引：6
|
作者：
Plebanski, Magdalena [2 ]
Katsara, Maria [1 ]
Sheng, Kuo-ching [1 ]
Xiang, Sue Dong [2 ]
Apostolopoulos, Vasso [1 ]
机构：
[1] Burnet Inst, Ctr Immunol, Immunol & Vaccine Lab, Melbourne, Vic 3004, Australia
[2] Monash Univ, Melbourne, Vic 3181, Australia
来源：
EXPERT REVIEW OF VACCINES | 2010年 / 9卷 / 06期
关键词：
antigen delivery; cellular responses; cytotoxic T lymphocyte; cytotoxic T lymphocyte precursor; immunotherapy; OTI; OTII; proliferation; T cell; vaccine; PLASMODIUM-FALCIPARUM; IMMUNE-RESPONSES; IN-VIVO; FUSION PROTEIN; TUMOR-ANTIGEN; GRANZYME-B; IFN-GAMMA; CTL ASSAY; LYMPHOCYTES; MANNAN-MUC1;
D O I：
10.1586/ERV.10.53
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
A successful vaccine for immunotherapy, particularly for solid tumors or viral infections, requires a suitable target antigen and the production of a cytotoxic T-cell response. In addition, CD4 T cells play an important role in cellular immunity. Here, we briefly discuss methods by which T cells are measured in vitro after vaccination.
引用
收藏
页码：595 / 600
页数：6
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