Safety, Efficacy, and Indications of β-Adrenergic Receptor Blockade to Reduce Heart Rate prior to Coronary CT Angiography

被引：80

作者：

Mahabadi, Amir A. ^{[1
]}

Achenbach, Stephan ^{[2
]}

Burgstahler, Christof ^{[3
]}

Dill, Thorsten ^{[4
]}

Fischbach, Roman ^{[5
]}

Knez, Andreas ^{[6
]}

Moshage, Werner ^{[7
]}

Richartz, Barbara M. ^{[8
]}

Ropers, Dieter ^{[2
]}

Schroeder, Stephen ^{[9
]}

Silber, Sigmund ^{[8
]}

Moehlenkamp, Stefan ^{[1
]}

机构：

[1] Univ Clin Duisburg Essen, W German Heart Ctr, Dept Cardiol, D-45122 Essen, Germany

[2] Univ Erlangen Nurnberg, Dept Cardiol, Erlangen, Germany

[3] Univ Tubingen, Dept Internal Med Sports Med, Tubingen, Germany

[4] Sana Kliniken Dusseldorf, Dusseldorf, Germany

[5] Asklepios Klin Altona, Dept Radiol Neuroradiol & Nucl Med, Hamburg, Germany

[6] Klinikum Weilheim, Dept Cardiol, Weilheim, Germany

[7] Klinikum Traunstein, Dept Internal Med Cardiol, Traunstein, Germany

[8] Heart Diagnost Ctr, Munich, Germany

[9] Klin Eichert, Dept Cardiol, Goppingen, Germany

来源：

RADIOLOGY | 2010年 / 257卷 / 03期

关键词：

SOURCE COMPUTED-TOMOGRAPHY; LEFT-VENTRICULAR FUNCTION; TUBE CURRENT MODULATION; ACUTE CHEST-PAIN; DUAL-SOURCE; DIAGNOSTIC-ACCURACY; IMAGE QUALITY; CARDIAC CT; MYOCARDIAL-INFARCTION; INHIBITOR IVABRADINE;

D O I：

10.1148/radiol.10100140

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

For selected indications, coronary computed tomographic (CT) angiography is an established clinical technology for evaluation in patients suspected of having or known to have coronary artery disease. In coronary CT angiography, image quality is highly dependent on heart rate, with heart rate reduction to less than 60 beats per minute being important for both image quality and radiation dose reduction, especially when single-source CT scanners are used. beta-Blockers are the first-line option for short-term reduction of heart rate prior to coronary CT angiography. In recent years, multiple beta-blocker administration protocols with oral and/or intravenous application have been proposed. This review article provides an overview of the indications, efficacy, and safety of beta-blockade protocols prior to coronary CT angiography with respect to different scanner techniques. Moreover, implications for radiation exposure and left ventricular function analysis are discussed. (C)RSNA, 2010

引用

页码：614 / 623

页数：10

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