Synthesis and properties of 3-acyl-γ-pyrones, a novel class of flavones and chromones

被引:63
作者
Ganguly, AK [1 ]
Kaur, S
Mahata, PK
Biswas, D
Pramanik, BN
Chan, TM
机构
[1] Stevens Inst Technol, Hoboken, NJ 07030 USA
[2] Schering Plough Corp, Inst Res, Kenilworth, NJ 07033 USA
关键词
synthesis; heterocycles;
D O I
10.1016/j.tetlet.2005.04.010
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Using modified Baker-Venkataraman reaction a novel class of 3-acyl flavones and chromones have been synthesised. Reaction mechanism for their formation have been elucidated. The properties of 3-acyl flavonoids indicate them to be precursors for the synthesis of flavones. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码:4119 / 4121
页数:3
相关论文
共 7 条
  • [1] Molecular rearrangement of some o-acyloxyacetophenones and the mechanism of the production of 3-acylchromones
    Baker, W
    [J]. JOURNAL OF THE CHEMICAL SOCIETY, 1933, : 1381 - 1389
  • [2] HIRAO I, 1984, SYNTHESIS-STUTTGART, P1076
  • [3] Cancer preventive effects of flavonoids - a review
    Le Marchand, L
    [J]. BIOMEDICINE & PHARMACOTHERAPY, 2002, 56 (06) : 296 - 301
  • [4] Synthetical experiments in the chromone group Part XIV The action of sodamide on l-acyloxy-2-acetonaphthones
    Mahal, HS
    Venkataraman, K
    [J]. JOURNAL OF THE CHEMICAL SOCIETY, 1934, : 1767 - 1769
  • [5] Dietary bioflavonoids induce apoptosis in human leukemia cells
    Matsui, J
    Kiyokawa, N
    Takenouchi, H
    Taguchi, T
    Suzuki, K
    Shiozawa, Y
    Saito, M
    Tang, WR
    Katagiri, YU
    Okita, H
    Fujimoto, J
    [J]. LEUKEMIA RESEARCH, 2005, 29 (05) : 573 - 581
  • [6] Riva C, 1997, SYNTHESIS-STUTTGART, P195
  • [7] Cyclin-dependent kinases: Initial approaches to exploit a novel therapeutic target
    Sausville, EA
    Zaharevitz, D
    Gussio, R
    Meijer, L
    Louarn-Leost, M
    Kunick, C
    Schultz, R
    Lahusen, T
    Headlee, D
    Stinson, S
    Arbuck, SG
    Senderowicz, A
    [J]. PHARMACOLOGY & THERAPEUTICS, 1999, 82 (2-3) : 285 - 292