Detection of Wolbachia genes in a patient with non-Hodgkin's lymphoma

被引：9

作者：

Chen, X. -P. ^{[1
]}

Dong, Y. -J. ^{[2
]}

Guo, W. -P. ^{[1
]}

Wang, W. ^{[1
]}

Li, M. -H. ^{[1
]}

Xu, J. ^{[1
]}

Dumler, J. S. ^{[3
,4
]}

Zhang, Y. -Z. ^{[1
]}

机构：

[1] Chinese Ctr Dis Control & Prevent, State Key Lab Infect Dis Prevent & Control, Collaborat Innovat Ctr Diag & Treatment Infect Di, Dept Zoonoses,Natl Inst Communicable Dis Control, Beijing, Peoples R China

[2] Peking Univ, Dept Haematol, Hosp 1, Beijing, Peoples R China

[3] Univ Maryland, Sch Med, Dept Pathol, Baltimore, MD 21201 USA

[4] Univ Maryland, Sch Med, Dept Microbiol & Immunol, Baltimore, MD 21201 USA

来源：

CLINICAL MICROBIOLOGY AND INFECTION | 2015年 / 21卷 / 02期

基金：

中国国家自然科学基金;

关键词：

Infection; non-Hodgkin lymphoma; Wolbachia agent; REAL-TIME PCR; PIPIENTIS;

D O I：

10.1016/j.cmi.2014.09.008

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Wolbachia 16S rRNA and fbpA genes were twice detected over 5 days in the blood of a patient with high fever. The patient was given fluoroquinolones and the fever resolved. Four weeks later, he was diagnosed with non-Hodgkin's lymphoma and received R-CHOP (Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, Prednisolone) treatment resulting in complete remission. This is the first report of detection of Wolbachia genes from the blood of human patients with non-Hodgkin's lymphoma. Clinical Microbiology and Infection (C) 2014 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

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收藏

页码：182.e1 / 182.e4

页数：4

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