The cardiac effects of hydroxychloroquine in immune-mediated rheumatologic diseases

被引：0

作者：

Weidman-Evans, Emily ^{[1
]}

Porter, Mandy ^{[1
]}

机构：

[1] Louisiana State Univ, Hlth Sci Ctr, PA Program, New Orleans, LA 70112 USA

来源：

JAAPA-JOURNAL OF THE AMERICAN ACADEMY OF PHYSICIAN ASSISTANTS | 2022年 / 35卷 / 04期

关键词：

hydroxychloroquine; cardiac; adverse reactions; rheumatoid arthritis; systemic lupus erythematosus; chloroquine; CARDIOVASCULAR-DISEASE; ARTHRITIS; CHLOROQUINE; RISK;

D O I：

10.1097/01.JAA.0000805852.13262.54

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Hydroxychloroquine, when used to treat patients with rheumatoid arthritis or systemic lupus erythematosus, has been found to reduce cardiovascular disease (CVD). The drug also has been associated with cardiac adverse reactions such as conduction abnormalities. This article reviews the reduction of CVD and the cardiac adverse reactions associated with hydroxychloroquine.

引用

页码：51 / 53

页数：3

共 15 条

[1] Risk of Cardiovascular Mortality in Patients With Rheumatoid Arthritis: A Meta-Analysis of Observational Studies [J].

Avina-Zubieta, J. Antonio ;

Choi, Hyon K. ;

Sadatsafavi, Mohsen ;

Etminan, Mahyar ;

Esdaile, John M. ;

Lacaille, Diane .

ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH, 2008, 59 (12) :1690-1697

[2] Race/Ethnicity and Cardiovascular Events Among Patients With Systemic Lupus Erythematosus [J].

Barbhaiya, Medha ;

Feldman, Candace H. ;

Guan, Hongshu ;

Gomez-Puerta, Jose A. ;

Fischer, Michael A. ;

Solomon, Daniel H. ;

Everett, Brendan ;

Costenbader, Karen H. .

ARTHRITIS & RHEUMATOLOGY, 2017, 69 (09) :1823-1831

[3] Cardiac Complications Attributed to Chloroquine and Hydroxychloroquine: A Systematic Review of the Literature [J].

Chatre, Clotilde ;

Roubille, Francois ;

Vernhet, Helene ;

Jorgensen, Christian ;

Pers, Yves-Marie .

DRUG SAFETY, 2018, 41 (10) :919-931

[4] Ethnic Disparities in Atherosclerotic Cardiovascular Disease Incidence and Prevalence Among Rheumatoid Arthritis Patients in the United States: a Systematic Review [J].

Daniel, Christina M. ;

Davila, Lesley ;

Makris, Una E. ;

Mayo, Helen ;

Caplan, Liron ;

Davis, Lisa ;

Solow, E. Blair .

ACR OPEN RHEUMATOLOGY, 2020, 2 (09) :525-532

[5] Revisiting hydroxychloroquine and chloroquine for patients with chronic immunity-mediated inflammatory rheumatic diseases [J].

dos Reis Neto, Edgard Torres ;

Kakehasi, Adriana Maria ;

Pinheiro, Marcelo de Medeiros ;

Ferreira, Gilda Aparecida ;

Lopes Marques, Claudia Diniz ;

Henrique da Mota, Licia Maria ;

Paiva, Eduardo dos Santos ;

Salviato Pileggi, Gecilmara Cristina ;

Sato, Emilia Inoue ;

Monteiro Gomides Reis, Ana Paula ;

Xavier, Ricardo Machado ;

Provenza, Jose Roberto .

ADVANCES IN RHEUMATOLOGY, 2020, 60 (01)

[6] Toxicity of chloroquine and hydroxychloroquine following therapeutic use or overdose [J].

Doyno, Cassandra ;

Sobieraj, Diana M. ;

Baker, William L. .

CLINICAL TOXICOLOGY, 2021, 59 (01) :12-23

[7] Rheumatoid Arthritis Disadvantages Younger Patients for Cardiovascular Diseases: A Meta-Analysis [J].

Fransen, Jaap ;

Kazemi-Bajestani, Seyyed M. R. ;

Bredie, Sebastian J. H. ;

Popa, Calin D. .

PLOS ONE, 2016, 11 (06)

[8] Cardiovascular disease in systemic lupus erythematosus: A comprehensive update [J].

Giannelou, Mayra ;

Mavragani, Clio P. .

JOURNAL OF AUTOIMMUNITY, 2017, 82 :1-12

[9] Chloroquine and hydroxychloroquine are associated with reduced cardiovascular risk: a systematic review and meta-analysis [J].

Liu, Dan ;

Li, Xiaodan ;

Zhang, Yonggang ;

Kwong, Joey Sum-Wing ;

Li, Ling ;

Zhang, Yiyi ;

Xu, Chang ;

Li, Qianrui ;

Sun, Xin ;

Tian, Haoming ;

Li, Sheyu .

DRUG DESIGN DEVELOPMENT AND THERAPY, 2018, 12 :1685-1695

[10]

Myasoedova E, 2018, ARTHRITIS RHEUMATOL, V70

← 1 2 →