Senolytics against Covid-19?

被引：0

作者：

Jordan, Bertrand ^{[1
]}

机构：

[1] Aix Marseille Univ, ADES Anthropol Bioculturelle Droit Eth & Sante, Etab Francais Sang CoReBio PACA, UMR CNRS 7268, Case 901,Parc Sci Luminy, F-13288 Marseille 09, France

来源：

M S-MEDECINE SCIENCES | 2021年 / 37卷 / 11期

关键词：

D O I：

10.1051/medsci/2021161

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The elimination of some senescent cells by "senolytic" compounds can greatly improve the health of aged mice and in some cases reverse the effects of aging. Using a microbial exposure system that closely models coronavirus infection, it is possible to largely protect old mice from the effects of viral infection. This immediately suggests clinical application of the approach, and is the aim of ongoing phase II clinical trials in Covid-19 patients.

引用

页码：1062 / 1065

页数：4

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