Case report: Postoperative abdominal recurrence of pulmonary pleomorphic carcinoma showed a dramatic response to S-1 after pembrolizumab

被引：1

作者：

Kojima, Yuichi ^{[1
]}

Takeyabu, Kimihiro ^{[1
]}

Kimura, Mizuki ^{[1
]}

Matunaga, Akihiro ^{[1
]}

Kudou, Jyunya ^{[1
]}

Ohata, Yoshihiro ^{[1
]}

Satoh, Miki ^{[1
]}

Tobioka, Hirotoshi ^{[2
]}

Ishikawa, Keidai ^{[3
]}

Kawamura, Takeshi ^{[3
]}

机构：

[1] Otaru Kyokai Hosp, Dept Resp Med, Otaru, Hokkaido, Japan

[2] Otaru Kyokai Hosp, Dept Diagnost Pathol, Otaru, Hokkaido, Japan

[3] Otaru Kyokai Hosp, Dept Thorac Surg, Otaru, Hokkaido, Japan

来源：

RESPIRATORY MEDICINE CASE REPORTS | 2021年 / 34卷

关键词：

Pulmonary pleomorphic carcinoma; S-1; Pembrolizumab; Second line treatment; Programmed cell death ligand 1; Tegafur; CHEMOTHERAPY; NIVOLUMAB; EFFICACY; THERAPY;

D O I：

10.1016/j.rmcr.2021.101501

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

The patient was an 80-year-old woman with combined pulmonary fibrosis and emphysema. She was diagnosed with pulmonary pleomorphic carcinoma in the right upper lobe, which relapsed 18 months after the operation. Computed tomography showed a mass in contact with the posterior wall of the lower part of the stomach. The patient was treated with two cycles of pembrolizumab, but the disease progressed. She was treated with S-1 as second-line therapy, resulting in tumor-shrinking after two cycles. Progression was not observed over the next twelve months. We report a rare case involving S-1 after immune checkpoint inhibitor treatment.

引用

页数：4

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