What is the optimal initiation timing of angiotensin converting enzyme inhibitor treatment for maximum benefits in acute myocardial infarction patients?

被引:0
|
作者
Yan Hong-bing [1 ,2 ,3 ]
Wang Shao-ping [4 ]
机构
[1] Chinese Acad Med Sci, Coronary Heart Dis Ctr, Cardiovasc Inst, Beijing 100037, Peoples R China
[2] Chinese Acad Med Sci, Fu Wai Hosp, Beijing 100037, Peoples R China
[3] Peking Union Med Coll, Beijing 100037, Peoples R China
[4] Capital Med Univ, Div 28, Beijing Anzhen Hosp, Beijing 100029, Peoples R China
关键词
angiotensin-converting enzyme inhibitor; acute myocardial infarction; left ventricular remodeling; LEFT-VENTRICULAR DYSFUNCTION; INTRACORONARY ENALAPRILAT; THROMBOLYSIS; CAPTOPRIL; MORTALITY; FOSINOPRIL; MORBIDITY; SURVIVAL;
D O I
10.3760/cma.j.issn.0366-6999.2011.03.026
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Randomized clinical trials led to the clinical recommendation that angiotensin-converting enzyme inhibitors (ACEI) should be used as standard therapy in most patients experiencing an acute myocardial infarction (AMI). However, the optimal initiation timing of treatment, as well as the exact mechanisms, have not been completely resolved, especially with the development of reperfusion strategy after AMI. Earlier initiation of ACEI might be associated with more prompt recovery of left ventricular ejection fraction due to more rapid attenuation of negative remodeling. Chin Med J 2011;124(3):464-466
引用
收藏
页码:464 / 466
页数:3
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