Advanced Laser System for 3D Optoacoustic Tomography of the Breast

被引：11

作者：

Klosner, Marc ^{[1
]}

Chan, Gary ^{[1
]}

Wu, Chunbai ^{[1
]}

Heller, Donald F. ^{[1
]}

Su, Richard ^{[2
]}

Ermilov, Sergey ^{[2
]}

Brecht, Hans Peter ^{[2
]}

Ivanov, Vassili ^{[2
]}

Talole, Pratik ^{[2
]}

Lou, Yang ^{[3
]}

Anastasio, Mark ^{[3
]}

Oraevsky, Alexander ^{[2
]}

机构：

[1] Light Age Inc, Somerset, NJ 08873 USA

[2] Tomowave Labs, Houston, TX 77081 USA

[3] Washington Univ, St Louis, MO 63130 USA

来源：

PHOTONS PLUS ULTRASOUND: IMAGING AND SENSING 2016 | 2016年 / 9708卷

关键词：

Optoacoustic imaging; alexandrite laser; pulsed laser; mammography; tomography; breast cancer; tumor; photoacoustic imaging;

D O I：

10.1117/12.2209398

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

We describe the ongoing development and performance of a high-pulse-energy wavelength-cycling laser system for three-dimensional optoacoustic tomography of the breast. Joule-level energies are desired for achieving the required penetration depths while maintaining safe fluence levels. Wavelength cycling provides a pulse sequence which repeatedly alternates between two wavelengths (approximately 756 and 797 nm) that provide differential imaging. This improves co-registration of captured differential images and quantification of blood oxygen saturation. New design features have been developed for and incorporated into a clinical prototype laser system, to improve efficacy and ease of use in the clinic. We describe the benefits of these features for operation with a clinical pilot optoacoustic / ultrasound dual-modality three-dimensional imaging system.

引用

页数：14

共 32 条

[1] An ultrasound cylindrical phased array for deep heating in the breast: theoretical design using heterogeneous models [J].