A novel three-component method for the synthesis of triazolo[1,2-a]indazole-triones

被引：83
作者：
Bazgir, Ayoob [1 ]
Seyyedhamzeh, Mozhdeh [1 ]
Yasaei, Zahra [1 ]
Mirzaei, Peiman [1 ]
机构：
[1] Shaheed Beheshti Univ Med Sci, Dept Chem, Tehran, Iran
来源：
TETRAHEDRON LETTERS | 2007年 / 48卷 / 50期
关键词：
dimedone; urazole; triazoloindazole; one-pot reaction;
D O I：
10.1016/j.tetlet.2007.10.084
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient synthesis of triazolo[1,2-a] indazole-1,3,8-trione derivatives based on the three-component condensation of urazole, dimedone and aromatic aldehydes under solvent-free conditions is described. (C) 2007 Published by Elsevier Ltd.
引用
收藏
页码：8790 / 8794
页数：5
相关论文
共 28 条
  • [1] Tangstophosphoric acid (H3PW12O40):: An efficient and eco-friendly catalyst for the one-pot synthesis of dihydropyrimidin-2(1H)-ones
    Amini, Mostafa Mohammadpour
    Shaabani, Ahmad
    Bazgir, Ayoob
    [J]. CATALYSIS COMMUNICATIONS, 2006, 7 (11) : 843 - 847
  • [2] Multiple-component condensation strategies for combinatorial library synthesis
    Armstrong, RW
    Combs, AP
    Tempest, PA
    Brown, SD
    Keating, TA
    [J]. ACCOUNTS OF CHEMICAL RESEARCH, 1996, 29 (03) : 123 - 131
  • [3] Asymmetric synthesis of (3S,4R,5R)-4,5-dihydroxy-3-methyl-2,3,4,5-tetrahydropyridazine:: a formal synthesis of 1-azagulofagomine analogues
    Arroyo, Y
    Rodríguez, JF
    Santos, M
    Tejedor, MAS
    Vaca, I
    Ruano, JLG
    [J]. TETRAHEDRON-ASYMMETRY, 2004, 15 (06) : 1059 - 1063
  • [4] Synthesis of novel lactam derivatives and their evaluation as ligands for the dopamine receptors, leading to a D4-selective ligand
    Awadallah, Fadi M.
    Mueller, Franziska
    Lehmann, Jochen
    Abadi, Ashraf H.
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY, 2007, 15 (17) : 5811 - 5818
  • [5] Rapid synthesis of VX-745: p38 MAP kinase inhibition in Werner syndrome cells
    Bagley, Mark C.
    Davis, Terence
    Dix, Matthew C.
    Rokicki, Michal J.
    Kipling, David
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2007, 17 (18) : 5107 - 5110
  • [6] High-throughput synthesis and optimization of thrombin inhibitors via urazole α-addition and Michael addition
    Boatman, PD
    Urban, J
    Nguyen, M
    Qabar, M
    Kahn, M
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2003, 13 (08) : 1445 - 1449
  • [7] Solid-phase library synthesis of triazolopyridazines via [4+2] cycloadditions
    Boldi, AM
    Johnson, CR
    Eissa, HO
    [J]. TETRAHEDRON LETTERS, 1999, 40 (04) : 619 - 622
  • [8] Synthesis and biological activities of new checkpoint kinase 1 inhibitors structurally related to granulatimide
    Conchon, Elisabeth
    Anizon, Fabrice
    Aboab, Bettina
    Prudhomme, Michelle
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2007, 50 (19) : 4669 - 4680
  • [9] Craig P. N., 1991, COMPREHENSIVE MED CH, V8
  • [10] A novel and efficient synthesis of pyrimido[4,5-d]pyrimidine-2,4,7-trione and pyrido[2,3-d:6,5-d] dipyrimidine-2,4,6,8-tetrone derivatives
    Dabiri, Minoo
    Arvin-Nezhad, Harnid
    Khavasi, Hamid Reza
    Bazgir, Ayoob
    [J]. TETRAHEDRON, 2007, 63 (08) : 1770 - 1774
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